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《糖尿病胰島素治療方案（insulin therapy for diabetes mellitus）》由會(huì)員上傳分享，免費(fèi)在線閱讀，更多相關(guān)內(nèi)容在教育資源-天天文庫。
1、糖尿病胰島素治療方案（Insulintherapyfordiabetesmellitus）ThediabeticinsulintherapySelectionofinsulintypes*animalinsulinisextractfromanimalpancreaspurifiedthroughaseriesofprocessessuchasproduction,thepeoplebelongstotheheterogeneousproteinhasstrongimmunogenicityandmaycausesensitization,long-termusemayha
2、veledtoreducedefficacyofantibody.Recombinanthumaninsulinisabiologicalengineeringdrugproducedbygenerecombinationtechnology.Ithasthesamestructureandbiologicalactivityashumanendogenousinsulin.*recombinanthumaninsulinanaloguesofaminoacidstructureofaminoacidmodificationtechnologyofrecombinanthu
3、maninsulininthehumanbody,canchangethepharmacokinetics,accelerateorextendtheonsetordurationofactioninvivo,butbecauseofitsstructureandhumanendogenousinsulinisnotcompletelyconsistent,alsobelongtotheheterologouspolypeptideofpeopleitisimmunogenicandmaycausesensitization,orantibodiesleadtolessef
4、fective.Humaninsulinshouldbeusedinthefollowinggroups:AwomanwhohasbeenpregnantorintendingtohaveapregnancyAllergicpersonInsulinresistanceispresentinanimalsInsulintherapyhasjustbegunThosewhowishtoapplyinsulinintermittentlyLongtermuseofhumaninsulinanalogueswithreducedefficacyAnewpatientwhodoes
5、notknowthetypeofinsulinoriginallyusedInsulindeliveryregimen1,"insulinphysiologicalsupply"program,3~4injectionsperday(intensivetreatmentprogram)Fast/shortactinginsulin,premealinjection+medium/long-actinginsulin,beforegoingtobed,4injectionsperdayFast/shortactinginsulinisgiven3timesadaybefore
6、mealsBeforebreakfastandbeforedinner,takeaquick/shortactinginsulin+preoraloralhypoglycemicagent+bedtimemedium/long-actinginsulin,3timesadayPreinsulininjection+preinjection/shortactinginsulin+bedtimeinjection/medium/longactinginsulin,3injectionsperday,beforebreakfast2,1~2timesperdayinsulinin
7、jection(nonintensivetreatment)BIDOtreatment:bedtimeinjectionofmedium/longactinginsulin+oralhypoglycemicagentsduringthedayPremixedinsulinbeforebreakfast+premixedinsulinbeforedinnerBreakfast/quickactinginsulin+supper/shortactinginsulinBreakfastbeforespeed/shorta
