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1、單鼻孔經(jīng)蝶入路外科治療垂體瘤卒中療效觀察[摘要]目的:探討單鼻孔經(jīng)蝶入路外科治療垂體瘤卒中的優(yōu)點、治療效果。方法:將患有垂體瘤且具有可比性的80例臨床資料隨機分為兩組,每組40例,一組將其命名為經(jīng)蝶組,即使用單鼻孔經(jīng)蝶入路外科治療垂體瘤卒中;另一組則命名為傳統(tǒng)組,即使用傳統(tǒng)的經(jīng)顱手術治療垂體瘤卒中。并觀察手術情況,記錄術中出血量、手術時間、住院時間以及術后隨訪觀察記錄有無尿崩癥、腦脊液鼻漏等并發(fā)癥的發(fā)生并進行總結比較分析。結果:80例垂體瘤患者都挺順利的完成了手術。經(jīng)蝶組的手術時間、住院時間比傳統(tǒng)組短,術中出血量也比傳統(tǒng)組少,另外腦脊液漏、尿
2、崩癥、視力惡化等并發(fā)癥發(fā)生率也明顯低于傳統(tǒng)組,差異具有統(tǒng)計學意義(P<0.05)。結論:單鼻孔經(jīng)蝶入路外科治療垂體瘤卒中技術簡便、手術創(chuàng)傷小、安全性高、治療效果好、術后恢復快、并發(fā)癥少。[關鍵詞]垂體腫瘤;單鼻孔經(jīng)蝶入路;臨床療效Single-nostriltranssphenoidalroadsurgicaltreatmentofpituitaryapoplexyEfficacyofAbstractObjectivesExploretheadvantagesofasinglenostriltranssphenoidalsurgicaltre
3、atmentofpituitaryapoplexy,thetherapeuticeffect.MethodsSufferingfrompituitarytumorsandcomparable80casesclinicaldatawererandomlydividedintotwogroups,eachgroupof40cases,agroupnamedtranssphenoidalgroup,usingasinglenostriltranssphenoidalRoad,surgicaltreatmentofpituitarytumorapop
4、lexy;agroupnamedforthetraditionalgroup,andthattheuseoftranscranialsurgicaltreatmentofpituitaryapoplexy.Andobservethesurgicalsituation,recordedintraoperativebloodloss,operativetime,hospitalstay,andpostoperativefollow-uptoobservetheoccurrenceoftherecordwithorwithoutthecomplic
5、ationsofdiabetesinsipidus,cerebrospinalfluidrhinorrhea,andasummaryofcomparativeanalysis.Results80casesofpituitarytumorpatientsallcametoasmoothcompletionofthesurgery.Butterflygroup,operativetime,hospitalstayisshorterthanthetraditionalgroup,intraoperativebloodlosswaslessthant
6、hetraditionalgroup,additionofcerebrospinalfluidleakage,diabetesinsipidus,visualdeterioration,theincidenceofcomplicationswassignificantlylowerthanthetraditionalgroup,thedifferencewassignificance(P<0.05).ConclusionsSingle-nostriltranssphenoidalsurgicaltreatmentofpituitaryapop
7、lexytechnologyissimple,minimallyinvasive,safe,effectivetreatment,rapidpostoperativerecovery,fewercomplications.[Keywords]pituitarytumor;asinglenostriltranssphenoidal;clinicalefficacy垂體瘤通常又稱為垂體腺瘤,是一種臨床常見病,其發(fā)病率位居膠質(zhì)瘤和腦膜瘤之后,其占顱內(nèi)腫瘤的10%~15%,可引起諸如泌乳、男性乳房發(fā)育等內(nèi)分泌癥狀并且很多臟器均可能受到損害。目前垂體腺
8、瘤最主要也是最有效的方法就是用手術使腫瘤徹底清楚【1】。手術治療垂體瘤的最終目的是保護正常垂體功能、解除其對神經(jīng)組織的壓迫以及消除內(nèi)分泌癥狀。但隨著醫(yī)學水平的不斷發(fā)