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1、-目錄研究背景··························································································1參考文獻····················································································5第一部分：去分化間充質(zhì)干細胞生物學特性··············································9材料與方法··
2、··············································································10結(jié)果······················································································12討論······················································································14
3、參考文獻···················································································16第二部分：去分化間充質(zhì)干細胞體外成骨潛能分析····································17材料與方法················································································18結(jié)果······················
4、································································22第三部分：去分化間充質(zhì)干細胞體內(nèi)成骨潛能分析····································26材料與方法················································································27結(jié)果·············································
5、·········································31討論······················································································34參考文獻···················································································36結(jié)論和展望·································
6、·····················································41碩士研究生期間完成的論文·································································42中英文對照縮略詞表··········································································43致謝·······································
7、·····················································44--------細菌纖維素的生物相容性及聯(lián)合BMP2的成骨效應(yīng)研究背景研究背景間充質(zhì)干細胞(Mesenchymalstemcells,MSCs)來源于發(fā)育早期的中胚層和外胚層，最初在骨髓中被Friendenstein等發(fā)現(xiàn)為非造血組織干細胞，由于其具有可分化為間充質(zhì)組織細胞的能力，故稱之為間充質(zhì)干細胞[1]。以后陸續(xù)在許多組織中分離到，包括脂肪、滑膜、軟骨、骨膜、胎盤和臍血[2]。1.1間充質(zhì)干細胞生物學特
8、性間充質(zhì)干細胞具備以下共同屬性：(1)，間充質(zhì)干細胞是具有自我維持和自我更新的細胞群體，其細胞數(shù)目是相對恒定的，即間充質(zhì)干細胞具有自穩(wěn)定性。(2)，在生物體總的細胞構(gòu)成比上，間充質(zhì)干細胞只占有其中很小的一部分。(3)，間充質(zhì)干細胞可在適宜環(huán)境中向不同方向分化，即其為相對未分化類細胞[3]。1，MSCs具有強大的自我更新和多向分化能力?？梢苑只癁檐浌羌毎?、成骨
