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1、不同劑量地塞米松對羅哌卡因神經(jīng)阻滯作用的影張大志'王東信2王懷江'【摘要】目的比較不同劑最地塞米松復合羅哌卡因神經(jīng)阻滯對羅哌卡因阻滯時效的影響。方法60例患者隨機分為I、11、III三組,每組20例。所有患者均在神經(jīng)刺激器定位下行坐骨神經(jīng)復合腰叢阻滯麻醉。I組:1%羅哌卡因20ml加入生理鹽水30ml;II組:1%羅哌卡因20ml加入地塞米松5mg、生理鹽水29ml;III組:1%羅哌曰大
2、20ml加入地塞米松10mg>生理鹽水28ml0結(jié)果T組患者感覺阻滯持續(xù)時間和運動阻滯持續(xù)時間[腰從(7.8+4.2,5.7±3.l)h、坐骨神經(jīng)(&3±3.
3、6,6.5±3.8)h]明顯短于II組[腰叢(16.3+6.5,10.9±4.2)h、坐骨神經(jīng)(17.3±5.2,11.2±3.5)h]和III組[腰叢(24.2±5.8,14.6±5.1)h、坐骨神經(jīng)(24.7±4.4,13.6±4.8)h](A0.01),11組患者感覺阻滯持續(xù)吋間和運動阻滯持續(xù)時間明顯短于III組(/<0.01)。I組患者48h舒芬太尼的消耗量、按壓總次數(shù)和有效次數(shù)比TT.TTT組高(/K0.05)。結(jié)論5mg和10mg地塞米松均能延長0.4%羅哌卡因腰從-坐骨神經(jīng)阻滯作用時間,1Omg地塞米松較5mg地塞米松延長羅哌卡因作
4、用時間長?!娟P(guān)鍵詞】羅哌卡因,地塞米松,神經(jīng)阻滯Effectofdifferentdosesdexamethasoneonactionofropivacainej21ZhangDazhi/WangDongxinWangHuaijiangz1Departmentofanesthesiology,BeijingJiShuitanhospital,Beijing100035,China2Departmentofanesthesiology,ThefirsthospitalofPekingUniversity,Beijing100034,China[Ab
5、stract]objectiveTocompareeffectofdifferentdosesdexamethasoneontheactionofropivacaine.MethodsSixtypatientswererandomlyallocatedintothreegroupswith20caseseach?Guidedbyanervestimulator,lumbarplexuscombinedsciaticnerveblockwasperformedwithl%ropivacaine20mlplusnormalsaline(NS)30ml
6、ingroupI,l%ropivacaine20mlplusdexamethasone5mgandnormalsaline(NS)29mlingroupII,orl%ropivacaine20mlplusdexamethasonelOmgandnormalsaline(NS)28mlingroupIII.ResultsThedurationsofsensoryandmotorblockadeingroupIwere[lumbarplexus(7.8±4?2,5.7±3.1)handsciaticnerve(8.3±3.6,6?5±3?8)hJ,r
7、espectively,whichweresignificantlyshorterthan[(16.3±6.5,10.9+4.2)hand(17.3+5.2,11.2+3.5)hJingroupIIand[(24.2+5.8,14.6+5」)hand(24.7+4.4,13.6+4.8)h]ingroupIII(P<0.01).ThepostoperativesufentanilconsumptionandPCAbuttonpresstimesingroupIweremorethanthatofgroupIIandgroupIII(P<0.05)
8、at48hafteropcration.ConclusionDexamethasone5mgand1OmgsignificantlyprolongedtheactionofropivacaineinlumbarplexuscombinedsciaticnerveblockanddexamethasonelOmgprolongedtheactionofropivacainemorethanthatofdexamethasone5mg.【Keywords]ropivacaine,dexamethasone,nerveblock卜?肢骨科術(shù)后疼病往往被
9、患者描述為難以忍受特別是手術(shù)后的而二天是最痛的時期叫作者單位:1100035北京帀,北京積水潭醫(yī)院麻醉科2100034北京市,北人醫(yī)院麻