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1、LectureNotesModernOrganicSynthesisDaleL.BogerTheScrippsResearchInstituteCoordinatedbyRobertM.GarbaccioAssembledbyConformationalAnalysisStevenL.CastleKineticsandThermodynamicsRichardJ.LeeReactionMechanismsandConformationalEffectsOxidationReactionsandBryan
2、M.LewisAlcoholOxidationChristopherW.BoyceReductionReactionsandClarkA.SehonHydroborationReactionsMarcA.LabroliEnolateChemistryandJasonHongliuWuMetalationReactionsRobertM.GarbaccioKeyRingTransformationsWengeZhongJiyongHongBrianM.AquilaMarkW.LedeboerOlefinS
3、ynthesisGordonD.WilkieConjugateAdditionsRobertP.SchaumSyntheticAnalysisandDesignRobertM.GarbaccioCombinatorialChemistryJoelA.GoldbergTSRIPressLaJolla,CACopyright?1999TSRIPress.Allrightsreserved.Allrightsreserved.Nopartofthispublicationmaybereproduced,sto
4、redinaretrievalsystemortransmittedinanyformorbyanymeans:electronic,electrostatic,magnetictape,mechanical,photocopying,recordingorother-wise,withoutpermissioninwritingfromthepublisher.PrintFirstEdition1999CDVersion1.0(1999)CDVersion1.01(2000)CDVersion1.02
5、(2001)ISBNFlexicoverTheCDversionsoftheLectureNotes(Versions1.01and1.02)containcorrectionsandupdatestothescienceandwilldifferslightlyfromtheprintedtext(FirstEdition,1999).Weanticipatethatthiswillcontinueonanannualbasis,aswithanysetofclassroomlecturenotes.
6、Consequently,wewouldliketoencourageyoutoinformusofmistakesyoumightfindandwewelcomesuggestionsforadditionstothecontent.Infact,ifweareprovidedChemDrawfilesofscienceyouwouldliketoseeincluded,thebarrierstoitsincorporationareminimized.ThetextoftheCDmaybesearc
7、hedbyAdobeAcrobatReaderandthismaybeusedinlieuofanindex.PrintedandBoundintheU.S.A.byRushPress,SanDiego,CaliforniaIntroductionDaleL.BogerPrefaceThenoteshavebeenusedastheintroductorysectionofacourseonModernOrganicSynthesisthatcom-poses6weeksoralittlemoretha
8、none-halfofaquartercourseatTheScrippsResearchInstitute,DepartmentofChemistry.Consequently,anexhaustivetreatmentoftheindividualtopicsisbeyondthescopeofthisportionofthecourse.Theremaining4weeksofthequarterdelveintomoredetail