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1、LectureNotesModernOrganicSynthesisDaleL.BogerTheScrippsResearchInstituteCoordinatedbyRobertM.GarbaccioAssembledbyConformationalAnalysisStevenL.CastleKineticsandThermodynamicsRichardJ.LeeReactionMechanismsandConformationalEffectsOxidationReactionsandBryanM.LewisAlcoholOxidationChristopherW.BoyceRe
2、ductionReactionsandClarkA.SehonHydroborationReactionsMarcA.LabroliEnolateChemistryandJasonHongliuWuMetalationReactionsRobertM.GarbaccioKeyRingTransformationsWengeZhongJiyongHongBrianM.AquilaMarkW.LedeboerOlefinSynthesisGordonD.WilkieConjugateAdditionsRobertP.SchaumSyntheticAnalysisandDesignRobert
3、M.GarbaccioCombinatorialChemistryJoelA.GoldbergTSRIPressLaJolla,CACopyright?1999TSRIPress.Allrightsreserved.Allrightsreserved.Nopartofthispublicationmaybereproduced,storedinaretrievalsystemortransmittedinanyformorbyanymeans:electronic,electrostatic,magnetictape,mechanical,photocopying,recordingor
4、other-wise,withoutpermissioninwritingfromthepublisher.PrintFirstEdition1999CDVersion1.0(1999)CDVersion1.01(2000)CDVersion1.02(2001)ISBNFlexicoverTheCDversionsoftheLectureNotes(Versions1.01and1.02)containcorrectionsandupdatestothescienceandwilldifferslightlyfromtheprintedtext(FirstEdition,1999).We
5、anticipatethatthiswillcontinueonanannualbasis,aswithanysetofclassroomlecturenotes.Consequently,wewouldliketoencourageyoutoinformusofmistakesyoumightfindandwewelcomesuggestionsforadditionstothecontent.Infact,ifweareprovidedChemDrawfilesofscienceyouwouldliketoseeincluded,thebarrierstoitsincorporati
6、onareminimized.ThetextoftheCDmaybesearchedbyAdobeAcrobatReaderandthismaybeusedinlieuofanindex.PrintedandBoundintheU.S.A.byRushPress,SanDiego,CaliforniaIntroductionDaleL.BogerPrefaceThenoteshavebeenusedastheintroductorysectionofacourseonModernOrganicSynthesisthatcom-poses6weeksoralittlemorethanone
7、-halfofaquartercourseatTheScrippsResearchInstitute,DepartmentofChemistry.Consequently,anexhaustivetreatmentoftheindividualtopicsisbeyondthescopeofthisportionofthecourse.Theremaining4weeksofthequarterdelveintomoredetail
