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《木犀草素分子印跡聚合物微球的制備與應(yīng)用.研究》由會員上傳分享，免費(fèi)在線閱讀，更多相關(guān)內(nèi)容在教育資源-天天文庫。
1、AbstractMolecularimprintingtechniqueisanewtechnologywhichtheprinciplesimulatetotheinteractionbetweenantigenandantibody.Settingthetargetmoleculewhichneedtoseparateastemplate,throughthepolymerizationreactiontogetakindofpolymerwhichhavespecificselectivetoaparticularmatter.Thepreparationprocessea
2、sytocontrol,andpropertyissteady.Now,thetechnologyiswidelyused.Naturalproductsactiveingredientsisamainsourcewhichcouldpreventandcurethediseaseofhuman,andtheactiveingredientisbasisofthefunctionmatter.Luteolinisakindofflavonoidcompound,Thereareavarietyofpharmacologicalactivity,suchasantitumor,an
3、tivirus,oxidationresistance,fightbacteriumdiminishinflammation,etc.Peanutshellsisakindofcheapandrenewableabundantnaturalresource.Luteolin,amajorflavonoidinpeanuthull.Throughtheextractionandseparationtogethighpurityofluteolin,whichcouldbeusedforrawmaterialfordrugsorhealthfoods,havingabroadappl
4、icationprospectinthemarket.Thecontentsofthispapermainlyincludeaslist:1.Luteolinwasusedastemplatemolecule,undertheactionoffunctionalmonomerandcrosslinkingagent,addpolyethyleneglycol2000asdispersant,tolueneasporogenicagent,synthetizedluteolinmolecularlyimprintedpolymermicrospheresinthecondition
5、ofaqueoussolution.Thestructureofmolecularimprintingmicrosphereswerecharacterizedbyinfraredspectrometer,laserparticleanalyzer,Liquidnitrogenadsorptioninstrument,ect.Examinedthepreparationconditions’effecttotheadsorptionquantityandpolymermorphology,gainingthebetterpreparationconditions.2.Thesta
6、ticadsorptivemethodwasusedtoanalysetheadsorptionperformanceofluteolininthemolecularlyimprintedpolymermicrosphere.Theisothermaladsorptionindicatedthatthebiggestadsorptionquantitywasdifferentbetweenimprintedandnotimprintedmolecularlyimprintedpolymermicrospheres.Accordingtoscatchardequationanaly
7、siscouldbeinformedthat:incertainconcentrationrange,molecularlyimprintedpolymermicrosphereformedtwodifferentbindingsites.Throughcalculatingthebalanceequationofdissociationconstants,theresultswere0.2198mmol/Land2.7603mmol/L.Theisothermaladsorpt
