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1、沈陽藥科大學碩士學位論文摘要Abstract乃f6“Z淞五亨77留Jf尹‘西L.isanannualcreepingherbgrowingonroadsidesandhillsinChina.IntraditionalChinesemedicine,the丘.uitofZ胞,.愆s驢旭whichislcnownaS‘CiJiLi’'havelongbeenusedforthetreatmentofeyetrouble,edemaandabdominaIdistention,emissionandmorbidleucorrheaasweUaSVitiligo.InIndia,ithaslong
2、beenus酣asmedicineagainstimpotencyandcardioVasculardisease.ThecurrenttreatHlentforimpotency,“Tribestane”aIld“Vitanone’',aswellas掀tment五訂cardjoyaSculardisease.“T打busapon訪s’’a11d“Xin-nao·shu-tong”,arcallmadeofcrudesaponins仔om乃湯“,淞幼代sf廊.Fromthe75%ethanolextractofthe劬“sofZfP,-陀s驢西,17compoundswereisolate
3、dbymeansofsoIVentpartition,repeatedcolumnchromatographyonsilicagel,MPLC,HPLC.OnbaSisofphysico—chemicalpropertiesandspectroscopicanalysis,theirstmctureswereidentifiedasfollows.Steroidalglycosides:(23S,25S)-5僅一spirostan.24一one一3屈23一dihydroxy.3-D.{D—a-L-rh鋤nopyranoSyl一(1—2)一D-陟D-glucopyr肌osyl-(1—4)】-伊
4、D—galactopyranoside}(1),(24S,25S)一5僅-spirostan一筇,24-diol-3一D-{D—d—L—rh鋤nopyranosyl-(1—2)一D-眵一D-gluco.py啪osyl一(1—4)]壚一D—galactopyranoside)(2),hecogenin3一D-{D.a—L-rh鋤nopyranosyl一(1—2)一D-睜D-glucopyranosyl一(1—+4)】母D—galactopyranoside)(3),hecogenin3-0.{D節(jié)一D-glucopyranosyI-(1—2)·D.睜D-xylopyrallosyl-(1-÷3
5、)】·0哆D-gIucopyranosyl-(1—4)爭D—galactopy冊oside)(4),(25R)-5a—spirostan一12-one-2a,筇一dihydroXy(maJlogenin)3-D-{D彬-D·glucopyranosyl-(1—2)一D一睜D-Xylopyranosyl一(1—3)】-D毋D—glucopyranosyl一(1—4)伊D-galactop.yranoside}(5),26-D?∥-D-glucopy啪osyl一(25R)-5僅一f1們stan一12-one一3∥,22僅,26—triol一3·D-伊D·glucopyranosyl一(1_4)毋
6、D—galactopyralloside(6),26-D毋D—glucopymosyl一(25S)一5a一幾rostan-12-one一3肛22%26-仃iol-3一D.伊D—glucopyranosyl-(1_4)≯D-galactopyranoside(7),26一D侈-D—glucopyranoSyl-25(R)-5及一furoStan一12一one-筇,22a,26-triol一3一D.{D-僅一L-rhamnopyrallosyl一(1——}2)一I夕【伊D—glucopyranosyl-(1—÷4)】1伊D—galactopyranoside}(8),26一I:)—伊D—gluc
7、opyran‘osyl·25(S)-56c—fhrostan一2a,3∥,22僅,26-te仃aol一3·0哥D—glucopyranosyl一(1—2)侈D-glucopyrallosyl-(1_4)毋D—galaCtopyranoside(9),26一D伊D—glucopyranosyl一25(R)-5o【一凡rostan一2僅,3厲22a,26一te廿aol一3—0毋D-glucopyranosyl一(