資源描述:
《穩(wěn)心顆粒與比索洛爾聯用治療老年冠心病室性早搏的療效》由會員上傳分享,免費在線閱讀,更多相關內容在應用文檔-天天文庫。
1、【摘要】目的:觀察穩(wěn)心顆粒與比索洛爾聯用治療老年冠心病室性早搏的療效。方法:95例老年冠心病患者被隨機分為穩(wěn)心顆粒加比索洛爾組(A組,36例)、比索洛爾組(B組,31例)、穩(wěn)心顆粒組(C組,28例),觀察治療前后臨床癥狀和心律失常改善情況及不良反應。結果:治療前后動態(tài)心電圖觀察對比:A組總有效率為91.67%(33例),顯著高于B組的70.97%(22例),C組的71.43%(20例),P均<0.05,B組的總有效率與C組的比較無顯著性差異(P>0.05);治療后臨床癥狀改善情況:A組(94.44%)顯著高于B組(77.42%)、C
2、組(78.57%),P均<0.05;B組的與C組的比較則無顯著性差異(P>0.05)。結論:穩(wěn)心顆粒與比索洛爾聯用治療老年冠心病室性早搏的療效明顯優(yōu)于各自單用的療效。【關鍵詞】比索洛爾;冠狀動脈疾病;心律失?!herapeuticeffectofWenxingranulecombinedwithbisoprololonventricularprematurebeatinagedpatientswithcoronaryheartdisease/PANYongdong,JIANGBo,WANGShuqing//Department
3、ofCardiology,TheFirstPeople′sHospitalofQiqihaerCity,Qiqihaer,Heilongjiang,161000,China Abstract:Objective:ExploretheeffectofWenxingranulecombinedwithbisoprololonventricularprematurebeat(VPB)inagedpatientswithcoronaryheartdisease(CHD).Methods:The95agedCHDpatientswithVP
4、Bwererandomlydividedinto3groups:WenxinGranule+bisoprololgroup(groupA,36cases),bisoprololgroup(groupB,31cases),andWenxingranulegroup(groupC,28cases).TheclinicalsymptomsandVPBbeforeandafterwereobserved.Results:ComparedwithHoltermonitoringelectrocardiogrambeforeandaftersh
5、owedthatthetotaleffectiverateofgroupA,was91.67%(33cases),itwassignificantlymorethanthatofgroupB(70.97%,22cases)andgroupC(20cases,71.43%),P<0.05all,buttherewasnosignificantdifferencebetweengroupBandgroupC(P>0.05).Aftertreatment,theimprovementofclinicalsymptomsofgroupAwa
6、s94.44%,itwasalsosignificantlymorethanthatofgroupB(77.42%)andgroupC(78.57%),P<0.05all,buttherewasalsonosignificantdifferencebetweengroupBandgroupC(P>0.05).Conclusion:TheeffectiverateofWenxingranulecombinewithbisoprololissignificantlybetterthanthoseoftheiraloneinagedpat
7、ientswithcoronaryheartdiseaseandventricularprematurebeat. Keywords:Bisoprolol;Coronaryarterydisease;Arrhythmia 室性心律失常是臨床非常常見的心律失常,尤其易發(fā)于冠心病心肌缺血患者,輕者可引起心悸、胸悶、焦慮等不適,嚴重者可引起血流動力學改變,甚至誘發(fā)猝死。有效、安全地治療室性心律失常,不但可緩解患者的臨床癥狀,提高其生活質量,并且能降低惡性室性心律失常引起的猝死率,延長患者的壽命。穩(wěn)心顆粒是一種純中藥制劑,具有抗心律失常
8、、改善心肌供血、逆轉心肌肥厚等作用[1,2]。目前抗心律失常藥存在一些不足,故尋找療效好,且毒副作用少,長期使用不增加病死率的抗心律失常藥是國內外長期以來研究的重點。本研究采用穩(wěn)心顆粒與比索洛爾聯用和兩者單用作對照,探討穩(wěn)心顆粒與比索