柴桂消癭湯治療慢性淋巴細胞性甲狀腺炎的臨床觀察

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1、提要目的：觀察柴桂消癭湯治療慢性淋巴細胞性甲狀腺炎的臨床療效及對甲狀腺激素（FT3、FT4、TSH）和甲狀腺相關抗體（TPOAbTGAb）的影響。方法：將60例慢性淋巴細胞性甲狀腺炎患者隨機分為兩組，治療組予柴桂消癭湯配合西藥優(yōu)甲樂治療，對照組予西藥優(yōu)甲樂治療，30天為一個療程，連續(xù)治療兩個療程。觀察兩組治療前后的臨床癥狀體征、甲狀腺激素水平、甲狀腺自身抗體的水平。結果：臨床數據經統(tǒng)計學分析表明，治療組總有效率93.3%，對照組總有效率73.3%，總有效有率存在差異（P<0.05）。治療組和對照組治療前后癥狀均有改善，

2、治療組在改善頸部腫大、乏力癥狀、情緒低落方面作用更明顯，與對照組比較有差異，P<0.05。治療組和對照均能升高FT3、FT4，降低TSH，治療前后比較均差異，P<0.05；治療后組間比較無顯著性差異，P>0.05。在改善免疫指標方面，治療組和對照組均能降低甲狀腺相關抗體（TPOAbTGAb）水平，與治療前比較有統(tǒng)計學差異，P<0.05；治療后甲狀腺相關抗體（TPOAbTGAb）組間比較均有統(tǒng)計學差異。結論：柴桂消癭湯治療慢性淋巴細胞性甲狀腺炎療效確切，既能有效改善慢性淋巴細胞性甲狀腺炎患者的臨床癥狀，又能降低甲狀腺自身

3、抗體水平，控制疾病的發(fā)展。關鍵詞慢性淋巴細胞性甲狀腺炎；中醫(yī)藥療法；柴桂消癭湯TheClinicalObservationonTreatmentoftheChronicLymphocyticThyroiditiswiththeChaiGuiXiaoYingDecoctionSpeciality:InternalMedicineofTCMAuthor:MaoJianfangTutor:ProfessorSunFengleiAbstractObjects:ToobservetheeffectofChaiGuixiaoyin

4、gdecoctiononpatientswithChroniclymphocyticthyroiditisandtheinfluenceonthyroidhormonelevels,thyroid-associatedantibodieslevel.Methods:60patientswithChroniclymphocyticthyroiditsweredevidedintotreatmentgroup30casesand30casesofthecontrolgroup.Thetwoaregivenexcellent

5、musicianswith25-150ug，onetimeadayfor60days.ThetreatmentgroupalsotookChaiGuixiaoyingdecoctiontwotimesadayfor60days.Analyzingtheclinicalsymptomsandthelevelofthyroidhormone,TPOAbandTGAbbeforeandafteraperiodof60days’treatment.Results:Thetotaleffectiverateintreatment

6、groupwas93.3%,andthecontrolgroup’swas76.7%.ByRiditanalysis,thetreatmentgroupcomp-aredwiththecontrolgroupwassignificantlydifferent,P<0.05.Theclinicalsymptomsofthetwogroupsbecamebetter,andthetreatmentgroupdidgetbettereffectinswollenneckandfatigue.Bothgroups’medici

7、nescouldrisethehormonelevelofFT3FT4andcutdownthelevelofthyroidstimulatinghormone.Thedifferencesbeforeandafterthetreatmentwerebothstatisticallysignificant(P<0.05),thegroup’scomparisonisnotsignificantdifferent(P>0.05).Toimprovetheimmunetarget，duringthetreatmentgro

8、up,thereisdifferencebeforeandaftertreatment，P<0.05.Conclusions:ChaiGuixiaoyingdecoctioniseffectiveforChroniclymphocyticthyroidits,caneffectivelycontrolthesymptomsofCh