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《參苓白術(shù)散加減治療慢性腎衰竭脾胃損傷癥狀(脾腎氣虛型)的臨床研究》由會員上傳分享,免費在線閱讀,更多相關(guān)內(nèi)容在學(xué)術(shù)論文-天天文庫。
1、湖北中醫(yī)藥大學(xué)碩士學(xué)位論文參苓白術(shù)散加減治療慢性腎衰竭脾胃損傷癥狀(脾腎氣虛型)的臨床研究姓名:李曉迪申請學(xué)位級別:碩士專業(yè):中醫(yī)內(nèi)科學(xué)指導(dǎo)教師:薛莎20120528中文摘要目的:.現(xiàn)在越來越多的慢性腎衰竭(CRF)的患者有脾胃損傷的癥狀,如惡心、嘔吐、腹脹、納差等臨床癥狀,而這些癥狀同樣影響患者的腎功能,影響患者的生存生活質(zhì)量,本研究旨在觀察參苓白術(shù)散加減在治療慢性腎衰竭有脾胃損傷的癥狀的臨床療效,為患有該癥狀的患者減輕負(fù)擔(dān),提供有效的治療。,.方法:1.來自于武漢市一醫(yī)院門診和病房的60例診斷為慢性腎衰竭病人,并且有納差、惡心、嘔吐、腹瀉、腹脹等脾胃損傷的癥狀,分為治療組和對照組,每
2、組各30例,兩組中醫(yī)證型均為脾腎氣虛型,兩組都予以維持水電解質(zhì)平衡等西藥對癥支持治療,在此基礎(chǔ)上,一組予以加用參苓白術(shù)散加減口服中藥治療,而對照組不予以加服用中藥,兩組均一個月為一療程,兩組患者在年齡、性別、病程以及原發(fā)病等方面均無統(tǒng)計學(xué)差異。2.觀察兩組患者治療前后主要癥狀(如倦怠乏力,氣短懶言,食少納呆,惡心,嘔吐等)的變化,并進行臨床癥候積分量化,作療效分析。3.觀察患者的血肌酐,尿素氮等指標(biāo),于治療前后各檢查一次,比較療效。結(jié)果:1.兩組的總有效率分別為93.3%和63.3%,治療組的療效明顯優(yōu)于對照組。2.采用腎衰竭并且有脾胃癥狀的臨床癥狀分級量化表,所顯示加用參苓白術(shù)散的治療
3、組可明顯改善患者的脾胃損傷的癥狀觀察,明顯優(yōu)于對照組。3.從腎功能血肌酐(SCR)、尿素氮(BUN)等檢查結(jié)果上看,治療組的SCR、BUN降低明顯優(yōu)于對照組。結(jié)論:在治療慢性腎衰竭的有脾胃損傷的患者之中,加用參苓白術(shù)散可明顯改善患者的癥狀、生存質(zhì)量,而且在降低血肌酐和尿素氮,比對照組更有優(yōu)勢,相對的,加用參苓白術(shù)散組可延緩病情的發(fā)展。關(guān)鍵詞:參苓白術(shù)散慢性腎衰竭脾胃損傷臨床研究ToaddingandsubtractingSenIingBaizhuPowderinthetreatmentofthechronjCrenaIfaiIureWithspIeenandstomachsymptoms
4、injury(spIeenandkidneyemptytype)CIinicaIresearchSpeciaIity:InternaImediciReoftraditionaIChinesemediCiReAuthor:LiXiaodiTutor:Prof.XueshaABSTRACTPurpose.-Nowmoreandmorechronickidneyfailure(CRF)ofpatientswithsymptomsofspleenandstomachinjury,suchasnausea,vomiting,abdominaldistension,Poorappetite,clin
5、icalsymptoms,andthesesymptomscanalsoaffectpatientswithrenalfunction,affectsurvivalinpatientswiththequalityof1ife,theaimofthestudywastoobserveandSenlingBaizhupowderinthetreatmentofchronicrenalfailureandatasteoftheclinicalcurativeeffectofinjurysymptoms,withthesymptomsofthesepatientsreduceburden,and
6、provideeffectivetreatment.Methods:1.Fromahospitalinwuhancityoutpatientandward60casesofchronicrenalfailurediagnosisofpatients,andthereisnausea,vomiting,diarrhea,abdominaldistension,Poorappetiteofspleenandstomachinjurysuchasthesymptoms,dividedintothetreatmentgroupandcontrolgroup,eachgroupofeach30ca
7、ses,twogroupsofTCMsyndrometypearethespleendeficiencykidneytype,bothgroupsweremaintainedwaterelectrolytebalance,westernmedicinetreatmentofsymptomaticsupport,andbasedonthis,agroupoftoadda”senlingbaizhupowderandoralChines