notch1信號(hào)通路在顳葉癲癇發(fā)病中的作用及機(jī)制研究

notch1信號(hào)通路在顳葉癲癇發(fā)病中的作用及機(jī)制研究

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時(shí)間:2019-03-03

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1、分類號(hào)學(xué)號(hào)M201075180學(xué)校代碼10487密級(jí)碩士學(xué)位論文Notch1信號(hào)通路在顳葉癲癇發(fā)病中的作用及機(jī)制研究學(xué)位申請(qǐng)人:劉希金學(xué)科專業(yè):神經(jīng)病學(xué)指導(dǎo)教師:鄧學(xué)軍答辯日期:2013年5月11日ADissertationSubmittedinPartialFulfillmentoftheRequirementsfortheDegreeofMasterofmedicineIncreasedExpressionofNotch1inTemporalLobeEpilepsy:AbasedevidenceinAnimalandHumanCandidate:Li

2、uXijinMajor:NeurologySupervisor:DengXuejunHuazhongUniversityofScienceandTechnologyWuhan,Hubei430074,P.R.ChinaMay,2013獨(dú)創(chuàng)性聲明本人鄭重聲明,本學(xué)位論文是本人在導(dǎo)師指導(dǎo)下進(jìn)行的研究工作及取得的研究成果的總結(jié)。盡我所知,除文中已經(jīng)標(biāo)明引用的內(nèi)容外,本論文不包含任何其他個(gè)人或集體已經(jīng)發(fā)表或撰寫過(guò)的研究成果。對(duì)本文的研究做出貢獻(xiàn)的個(gè)人和集體,均已在文中以明確方式標(biāo)明。本人完全意識(shí)到本人將承擔(dān)本聲明引起的一切法律后果。學(xué)位論文作者簽名:日期:年月日

3、學(xué)位論文版權(quán)使用授權(quán)書本學(xué)位論文作者完全了解學(xué)校有關(guān)保留、使用學(xué)位論文的規(guī)定,即:學(xué)校有權(quán)保留并向國(guó)家有關(guān)部門或機(jī)構(gòu)送交論文的復(fù)印件和電子版,允許論文被查閱和借閱。本人授權(quán)華中科技大學(xué)可以將本學(xué)位論文的全部或部分內(nèi)容編入有關(guān)數(shù)據(jù)庫(kù)進(jìn)行檢索,可以采用影印、縮印或掃描等復(fù)制手段保存和匯編本學(xué)位論文。保密□,在_____年解密后適用本授權(quán)書。本論文屬于不保密□。(請(qǐng)?jiān)谝陨戏娇騼?nèi)打“√”)學(xué)位論文作者簽名:指導(dǎo)教師簽名:日期:年月日日期:年月日華中科技大學(xué)碩士學(xué)位論文目錄中英文對(duì)照表········································

4、················································1摘要·································································································3ABSTRACT··························································································5前言······························

5、···································································7材料方法···························································································91.實(shí)驗(yàn)動(dòng)物······················································································92.實(shí)驗(yàn)藥物·················

6、·····································································93.建立大鼠顳葉癲癇動(dòng)物模型······························································94.動(dòng)物分組·····················································································105.患者篩選··································

7、···················································106.腦電圖監(jiān)測(cè)··················································································117.行為學(xué)觀察··················································································118.組織切片處理·····································

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