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1、異位妊娠藥物治療中動態(tài)監(jiān)測血清孕酮水平的價值作者:杜敏霞,任利華,黃,林單位:新鄉(xiāng)醫(yī)學院護理學院,河南新鄉(xiāng)貴陽醫(yī)學院第一附屬醫(yī)院婦產(chǎn)科,貴州貴陽【摘要】目的分析異位妊娠患者藥物治療前后動態(tài)監(jiān)測血清孕酮水平的價值。方法84例采取藥物治療的異位妊娠患者分為治療成功組和治療失敗組,治療前、治療后3d、7d檢測比較2組血清孕酮、血清絨毛膜促性腺激素β(βHCG)。結(jié)果治療前和治療后3d治療成功組血清孕酮水平明顯低于治療失敗組(P<0.05),而2組間血清βHCG值的差異無統(tǒng)計學意義(P>0.05);治療后7d,治療
2、成功組血清孕酮值顯著低于治療失敗組(P<0.01),2組間血清βHCG值的差異也有統(tǒng)計學意義(P<0.05)。治療后3d和治療后7d治療成功組血清孕酮下降發(fā)生率均明顯高于治療失敗組(P<0.05)。治療后3d2組間血清βHCG下降發(fā)生率無明顯差異(P>0.05),而治療后7d治療成功組患者血清βHCG下降發(fā)生率明顯高于治療失敗組(P<0.05)。結(jié)論異位妊娠藥物治療前監(jiān)測血清孕酮水平有助于更有效地篩選藥物治療病例;治療后血清孕酮下降是迅速判斷藥物治療效果的靈敏指標?!娟P(guān)鍵詞】異位妊娠;孕酮;絨毛膜促性腺激素
3、;藥物療法ValueofserumprogesteronelevelswithdynamicmonitoringduringdrugtreatmentofpatientswithectopicpregnancyDUMinxia1,RENLihua1,HUANGLin2(1.DepartmentofNursing,XinxiangMedicalCollege,Xinxiang453003,China;2.theFirstAffiliatedHospitalofGuiyangMedicalCollege,Guiyang550000,China
4、)Abstract:ObjectiveToanalyzethevalueofserumprogesteronelevelswithdynamicmonitoringpreandpostdrugtreatmentonpatientswithectopicpregnancy.MethodsEightyfourpatientswithectopicpregnancy,whoweretreatmentwithdrug,weredividedintotreatmentsuccessfulgroupandtreatmentfaliuregroup.
5、Serumprogesteroneandchorionicgonadotrophinβweredetectedandcomparedbetweentwogroupspretreatmentandinthethirddayandtheseventhdayposttreatment.ResultsThelevelofserumprogesteroneintreatmentsuccessfulgroupwaslowerthanthatintreatmentfaliuregrouppretreatmentandinthethirdd
6、ayposttreatment(P<0.05),buttherewasnosignificantdifferenceofchorionicgonadotrophinβbetweentwogroups(P>0.05).Thelevelofserumprogesteroneintreatmentsuccessfulgroupwasobviouslylowerthanthatintreatmentfaliuregroupintheseventhdayposttreatment(P<0.01),andtherewassignifica
7、ntdifferenceofchorionicgonadotrophinβbetweentwogroups(P<0.05).Thedeclinerateofserumprogesteroneintreatmentsuccessfulgroupinthethirddayandintheseventhdayposttreatmentwassignificantlyhigherthanthatinthefailuretreatmentgroup(P<0.05),buttherewasnosignificantdifferenceofc
8、horionicgonadotrophinβbetweentwogroupinthethirddayposttreatment(P>0.05).The