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1、《回回藥方》失苔剌知丸治療腔隙性腦梗死患者認知功能障礙的療效觀察★付慧玲I李方2賈孟輝劉麗I曹麗翠I左艷麗“于凌志°李占濤°蘇丹°(1.寧夏醫(yī)科大學(xué)第二附屬醫(yī)院寧夏銀川7500012.銀川市興慶區(qū)永安中醫(yī)回醫(yī)醫(yī)院寧夏銀川7500003.回醫(yī)藥現(xiàn)代化省部共建教育部重點實驗室寧夏銀川7500044.寧夏醫(yī)科大學(xué)屮醫(yī)學(xué)院寧夏銀川750004)摘要:目的觀察失苔剌知丸治療腔隙性腦梗死患者認知功能障礙的臨床療效。方法將80例腔隙性腦梗死患者隨機分為對照組及治療組各40例,兩組患者合并有高血壓、糖尿病、高血脂者予對癥治療。對照組靜滴血栓通注射液50
2、0mg,每日1次,治療14天;治療組靜滴血栓通注射液,同時口服失苔刺知丸,1日2次,10g/次,治療14天;對兩組患者治療前和治療后進行蒙特利爾認知評估量表(MoCA)評分。結(jié)果治療麗兩組MoCA評分兩組差異無統(tǒng)計學(xué)意義(P>0.05);治療后治療組MoCA評分差異有統(tǒng)讓學(xué)意義(P<0.05;對照組治療前后無顯著差異(P>0.05)。結(jié)論冋藥方失苔剌知丸對腔隙性腦梗死患者認知功能障礙有明顯改善作用。關(guān)鍵詞:失苔剌知丸;腔隙性腦梗死;認知功能障礙;MoCAThecurativeeffectobservationofShidalazhiwa
3、ntreatmentonischemicstrokeofcognitivedisorderJaoYang1LiFang2JiaMenghui3CaoLicui3ZuoYanli4YuLinzhi4(l.TheShaPotouhospitalofNingxiaofZhongwei2.YonganhospitaloftraditionalChinesemedicineandHuimedicine3.Thefirstpeople'shospitalofYinchuan4.Ningxiamedicaluniversityinstituteoft
4、raditionalChinesemedicin)Abstract:objectiveToinvestigateThecurativeeffectobservationofShidalazhiwantreatmentonischemicstrokeofcognitivedisorde匚Methods80casesischemicstrokewererandomlydividedintothecontrolgroupandthetreatmentgroup,40casesineachgroup.Twogroupsofpatientswit
5、hhighbloodpressure,diabetes,hyperlipidemiatosymptomatictreatment.tthecontrolgroupweretreatmentwithXueShuanTonginjection500mg,onceperdayfor14days;thetreatmentgroupweregivenXueShuanTonginjectionandShidalazhiwan,1Og/time,twiceperdayfor14days.Cognitivefunctionandtheameliorat
6、ionofintelligencewereassessedbeforeandaftertreatment.ResultsThemontrealcognitiveassessmentofscorebothgroupsbeforetreatmenthadnosignificantdifference(P>0.()5).TreatmentgroupaftertreatmentofMoCAscoredifferencewasstatisticallysignificant(P<0.05);Thecontrolgroupbeforeandafte
7、rtreatmenthadnosignificantdifference(P>0.05).ConclusionTheShidalazhiwancanimprovethecognitionofthepatientswithcognitiveimpairmentaftercerebral★基金項目:國家自然科學(xué)基金(81260568);銀川市科技攻關(guān)課題(2012017)作者簡介:付慧玲,女,漢族,主治醫(yī)師,研究生,主要從事回醫(yī)藥防治腦血管疾病的臨床研究。infarction.KeyWords:TheShidalazhiwan、ischem
8、icstrokecognitivedisorder^MoCA血管性認知功能障礙是腦梗死患者臨床屮的常見并發(fā)癥之一,主要表現(xiàn)為記憶力明顯減退、注意力不集中、說話欠流利等,同時影響腦梗死后神經(jīng)功能損傷的恢復(fù)⑴。