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1、加味溫膽湯治療抑郁癥30例臨床觀察)摘要:[日的]觀察加味溫膽湯治療抑郁癥的臨床療效。[方法]將60例抑郁癥患者隨機(jī)分為屮藥組和対照組,対照組30例給予鹽酸氟西汀膠囊,屮藥組30例給予加味溫膽湯,兩組療程均為6周。治療前及治療后2,4,6周末采用漢密爾頓抑郁量表(HAMD)于進(jìn)行評(píng)分;治療前后采用屮醫(yī)癥候量表、神經(jīng)心理學(xué)測(cè)驗(yàn)、抗郁藥副反應(yīng)評(píng)定最表(SERS)評(píng)價(jià)療效和不良情況。[結(jié)果]治療6周后,屮藥組與対照組臨床療效和當(dāng),可明顯改善治療前HAMD評(píng)分,兩組未顯示統(tǒng)計(jì)學(xué)差異;中藥組在治療4周后對(duì)中醫(yī)癥候具有明顯改善作用,與對(duì)照組有明顯差異(P<0.05);兩組的基本執(zhí)行功能總分值存
2、在差異(P<0.05),主耍表現(xiàn)在WCST總正確數(shù)、TOH平均計(jì)劃時(shí)間、TMT-B錯(cuò)誤數(shù)方面屮約紐得分高于對(duì)照紐;中藥組的(SERS址表評(píng)分)不良反應(yīng)發(fā)生率(13.4%)明顯低于對(duì)照組(30.4%)。[結(jié)論]加味溫膽湯對(duì)抑郁癥具有良好的臨床治療效果。關(guān)鍵詞:抑郁癥;加味溫膽湯;緘西??;臨床觀察中圖分類(lèi)號(hào):R277.7ClinicalObservationofTreating30CasesofDepressionwithJiaweiWendanDecoctionTangJiuhuii,ZhangLipingi,WuPeiram,YanHong2(1.TianjinUniversity
3、ofTraditionalChineseMedicine,Humanisticmanagementcollege,Tianjin300073;2.FirstTeachingHospitalofTianjinUniversityofTraditionalChineseMedicine,TianJin300073)Abstract:Objective:ToinvestigatecurativeeffectoftreatingdepressionwithJiaweiWendanDecoction.Methods:60depressionpatientswererandomlydivide
4、dintotraditionalChinesemedicinegroupandcontrolgroup?Controlgroupof30patientsweretreatedwithFluoxetine;IraditionalChinesemedicinegroupof30patientsweretreatedwithJiaweiWendanDecoction.Bothgroupsweretreating6weeksasacourseoftreatment.Toevaluatecurativeeffectandsideeffect,Hamilton(HAMD)scalescorew
5、eremeasuredinbothgroupsbeforetreatmentandafterattheendofthe2nd,4th,6thweek,TCMsyndromes,neuropsychologicaltests,SERSweremeasuredinbothgroupsaftertreatment.Results:Attheendofthe6thweek,wefoundthattherewerenosignificantdifferencesbetweenthetwogroups(P>0.()5)inthecurativeeffectandthescoresofHAMD;
6、andfromthe4thweek,thechangesdifferencesofTCMsymptomsbetweentwogroupsweresignificant(P<0.05);andinthetraditionalChinesemedicinegroupthescoresofbasicneurocognitivefunctioning,suchasthecontinueerrorsofWCST,totalscoresofTOH,errorsofTMT-B,wereobviouslyhigherthanthecontrolgroup(P<0.05).Howcvcr,theex
7、tentofadversereaction(SERS)inthetraditionalChinesemedicinegroup(13.4%)waslowerthanthatinthecontrolgroup(30.4%).Conclusion:JiaweiWendanDecoctionhasagoodcurativeeffectintreatingdepression.Keywords:Depression;JiaweiWendanDecoction;Fluoxeti