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1、青蒿鱉甲湯聯(lián)合少量激素治療狼瘡性腎炎療效觀察［摘要］目的研究青蒿鱉甲湯聯(lián)合少量激素治療狼瘡性腎炎的臨床療效。方法62例狼瘡性腎炎患者均來至我院中醫(yī)科及血液科門診及住院部，按就診順序?qū)⑵潆S機分為治療組(32例)和對照組(30例)。治療組口服青蒿鱉甲湯聯(lián)合少量激素；對照組口服強的松片。結(jié)果治療組總有效率為90.6%,對照組總有效率為66.7%,治療組總有效率高于對照組(PV0.05)；經(jīng)過觀察，發(fā)現(xiàn)在臨床癥狀、激素撤減情況及藥物副作用方面，治療組明顯優(yōu)于對照組(P<0.05)o結(jié)論運用青蒿鱉甲湯聯(lián)合少
2、量激素治療狼瘡性腎炎，可明顯緩解臨床癥狀，改善實驗室指標，減少激素用量，穩(wěn)定病情和減少西藥的副作用。［關(guān)鍵詞］青蒿鱉甲湯；狼瘡性腎炎；強的松［中圖分類號］R593.242［文獻標識碼］A［文章編號］1673-7210(2012)08(b)-0112-02ClinicalobservationonQinghaoBiejiaDecoctioncombinedwithasmallamountofhormoneinthetreatmentoflupusnephritisWANGZhihuaDAIZhaoy
3、anQOANYaohuaTUYunZhanjiangCentralpeople'shospital,GuangdongProvince,Zhanjiang524037,China[Abstract]ObjectiveToobservetheclinicalefficacyofQinghaoBiejiaDecoctioncombinedwithasmallamountofhormoneinthetreatmentoflupusnephritis.Methods62patientswithlupusn
4、ephritiswerecomingtoourtraditionalChineseMedicineanddepartmentofhematologyinout-patientandin-pa.tientdepartment,weredividedintotwogroupsbyvisitingtheorderrandomly,thetreatmentgroupof32casesandthecontrolgroupof30cases.ThetreatmentgroupweretreatedwithQi
5、nghaoBiejiaDecoctioncombinedwithasmallamountofhormone；ThecontrolgroupweretreatedwithPrednisone?ResuItsThetotaleffectiverateofthetreatmentgroupwas90.6%,thetotaleffectiverateofthecontrolgroupwas66.7%,thetotaleffectiverateoftheteatmentgroupwashigherthant
6、hatofthecontrolgroup(P<0.05)；aftertheobservation,itwasfoundtha/tinclinicalsymptoms,hrmonereductionanddrugsideeffects,thetreatmentgroupwassignificantlybetterthanthecontrolgroup(P<0.05)?ConclusionUsingQinghaoBiejiaDecoctionwithasmallamountofhormonetotre
7、atlupusnephritis,canreduceclinicalsymptoms,improvelaboratoryparameters,reducehormonedosage,stabilizeenditionandreducethesideeffectsofWesternmedicine.[Keywords]Qinghaobiejiadecoction；Lupusnephritis；Prednisone系統(tǒng)性紅斑狼瘡(systemiclupuserythematosus,SLE)是一種多系
8、統(tǒng)損害，伴有多種自身抗體形成的免疫系統(tǒng)疾病，腎臟是常見受累器官，狼瘡性腎炎(lupusnephritis,LN)是免疫復(fù)合物沉淀引起的免疫性腎炎，筆者在臨床中運用青蒿鱉甲湯加減聯(lián)合少量激素治療狼瘡性腎炎，取得較好臨床療效，現(xiàn)報道結(jié)果如下：1資料與方法1.1一般資料62例狼瘡性腎炎患者均來自我院中醫(yī)科及血液科門診及住院部，按就診順序隨機分為兩組。治療組32例，男5例，女27例，男女比例1：5.4,平均年齡(31.38±10.85)歲,平均病程(2.70±0.58)年；對照組30例，男
