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1、LeyiWangEditorsAnimalCoronavirusesSPRINGERPROTOCOLSHANDBOOKSForfurthervolumes:http://www.springer.com/series/8623AnimalCoronavirusesEditedbyLeyiWangAnimalDiseaseDiagnosticLaboratory,OhioDepartmentofAgriculture,Reynoldsburg,OH,USAEditorLeyiWangAnimalDiseaseDiagnosticLaboratoryOhioDepartme
2、ntofAgricultureReynoldsburg,OH,USAISSN1949-2448ISSN1949-2456(electronic)SpringerProtocolsHandbooksISBN978-1-4939-3412-6ISBN978-1-4939-3414-0(eBook)DOI10.1007/978-1-4939-3414-0LibraryofCongressControlNumber:2016933865SpringerNewYorkHeidelbergDordrechtLondon?SpringerScience+BusinessMediaNe
3、wYork2016Thisworkissubjecttocopyright.AllrightsarereservedbythePublisher,whetherthewholeorpartofthematerialisconcerned,speci?callytherightsoftranslation,reprinting,reuseofillustrations,recitation,broadcasting,reproductiononmicro?lmsorinanyotherphysicalway,andtransmissionorinformationstor
4、ageandretrieval,electronicadaptation,computersoftware,orbysimilarordissimilarmethodologynowknownorhereafterdeveloped.Theuseofgeneraldescriptivenames,registerednames,trademarks,servicemarks,etc.inthispublicationdoesnotimply,evenintheabsenceofaspeci?cstatement,thatsuchnamesareexemptfromthe
5、relevantprotectivelawsandregulationsandthereforefreeforgeneraluse.Thepublisher,theauthorsandtheeditorsaresafetoassumethattheadviceandinformationinthisbookarebelievedtobetrueandaccurateatthedateofpublication.Neitherthepublishernortheauthorsortheeditorsgiveawarranty,expressorimplied,withre
6、specttothematerialcontainedhereinorforanyerrorsoromissionsthatmayhavebeenmade.Printedonacid-freepaperHumanaPressisabrandofSpringerSpringerScience+BusinessMediaLLCNewYorkispartofSpringerScience+BusinessMedia(www.springer.com)PrefaceThe?rstcoronavirus,avianinfectiousbronchitisvirus,wasisol
7、atedfromchickeneggsin1937.Porcinetransmissiblegastroenteritisvirusandmousehepatitisvirusweresubsequentlyidenti?edfrompigsandmice,respectively,inthe1940s.Inthefollowingdecades,whilethehumancoronaviruseswereidenti?edinthe1960s,otheranimalcoronavirusesincludingporcinehemaggl