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1、S8017thECCMID/25thICC,Oralpresentationsmortalityfromrecentlyemergeddiseasesvaries,rangingfromlessAresultofthedomesticanimalrevolutionisthattherehasneverbeforethan200peoplethusfarforH5N1avianin?uenzatoabout20millionforinhistorybeensomuchpoultryastoday.Thi
2、sfact,incombinationwithAIDS.Livestockproductionhasbeennegativelyaffectedbythedirectagrowingnumberofhumans,createsanarenawheredomesticanimals,mortalityofanimalsfromemerginginfectionsanddepopulationpolicieshumansand?nallyzoonoticpathogenscaninteract.In?uen
3、zaAvirustoprotectthesafetyofinternationaltradeandtocontrolthespreadofistheultimateactorinthisplaywheresomesubtypesmaychangeintopathogens.Theenvironmentalimpactofemerginginfectionsisofspecialhighlypathogenicforms.Thesemaybetransmitteddirectlytoman.concern
4、forendangeredwildanimalpopulations,whichcanbepushedAnotherworryingscenarioisthatanavianin?uenzaviruswillreassorttothebrinkofextinctionbysuchevents.Animals,andparticularlywildwithacirculatinghumanin?uenza.Agenetictraitmightthenreadilyanimals,arethoughttob
5、ethesourceofmorethan70%ofallemerginggofromthehumantothebirdvirussothatavianin?uenzaacquiresinfections(PhilosTransRSocLondonB356:983).Understandinghowthecapacitytopassfrompersontoperson.Withthisriskinmind,itsomeinfectiousagentshavebreachedthebarriersthatn
6、ormallylimitwouldadvisabletoconsideranymethodtoreducetheprobabilityofthisthisinterspeciestransmissionisimportant.However,thesebarriersarehappening.Contingencyplanningshouldtakeintoaccounttheknownpoorlycharacterised.Thehostspeciesbarrierforinfectioncanbed
7、e?nedevolutionarypotentialofanimalvirusesandotherpathogenstoadapttoasaninteractionoffactorsthatcollectivelylimitsthetransmissionoftheenvironmentofhumansanddomesticanimals.aninfectionfromonehostspecies(thedonorspecies)toanother(therecipientspecies)(Scienc
8、e312:394).SuchlimitingfactorsmayoccuratS392WildlifehostsofSARS-coronavirusandrelatedvirusesdifferentlevels,ofwhichthefunctionalcomponentsareorganism,tissue,andcell.Attheorganismlevel,barrierslimitingcontactbetweentwoL-F.Wa
