阿托伐他汀治療冠心病合并高脂血癥療效分析

《阿托伐他汀治療冠心病合并高脂血癥療效分析》由會員上傳分享，免費(fèi)在線閱讀，更多相關(guān)內(nèi)容在學(xué)術(shù)論文-天天文庫。

1、·334·西部醫(yī)學(xué)2014年3月第26卷第3期MedJWestChina，March2014，Vo1．26，No．3阿托伐他汀治療冠心病合并高脂血癥療效分析賴曉惠，李東，陳波(內(nèi)江市第三人民醫(yī)院心內(nèi)科，四川內(nèi)江641000)【摘要】目的觀察阿托伐他汀治療冠心病合并高脂血癥的臨床療效。方法回顧性分析我院收治的104例冠心病合并高脂血癥患者的臨床資料，根據(jù)治療方法不同分為治療組和對照組各52例，其中治療組患者采用阿托伐他汀治療，對照組患者采用辛伐他汀治療，比較兩組患者治療后的臨床效果、治療前后的血脂水平(TG、TC、LDL-C、HDL-C)以及

2、不良反應(yīng)發(fā)生情況。結(jié)果治療組患者的總有效率為86．54％，對照組患者的總有效率為75．0¨O，兩組間差異有顯著性(P0．05)；治療后8周，治療組患者的TG、TC、LDL-C水平均顯著低于對照組，HDL-C水平顯著高于對照組(均P<0．05)；治療組患者的不良反應(yīng)發(fā)生率為5．77，顯著低于對照組的不良反應(yīng)發(fā)生率(11．54，P

3、高脂血癥【中圖分類號】R541．4；R589．2【文獻(xiàn)標(biāo)志碼】Adoi：10．3959／j．issn．1672—3511．2014．03．025AnalysisofefficacyofatorvastatinintreatmentofcoronaryheartdiseasewithhyperlipidemiaLAIXiao-hui，LIDong，CHENBo(DepartmentofInternalMedicine，TheThirdPeopleHospitalofNeijiang，Neijiang641000，Sichuan，China)[

4、Abstract]ObjectiveToinvestigatetheclinicalefficacyforatorvastatininthetreatmentofcoronaryheartdiseasewithhyperlipidemia．MethodsTheclinicaldataof104caseswithcoronaryheartdiseasewithhyperlipidemiawastakenforretrospectiveanalysis．Accordingtothedifferenttreatmentmethods，theywe

5、redividedintothetreatmentgroupandthecontro1group，and52patientsineachgroup．Thetreatmentgroupwastakenwithatorvastatintreatment，andthecontro1groupwastakenwithsimvastatin．Theclinica1resultsaftertreatmentof1ipid1evels(TG，TC，LDL—C，HDL—C)，andadverseeventsofthetWOgroupswerecompare

6、d．ResultsThetotaleffectiverateinthetreatmentgroupwas86．54，andthetotaleffectiverateinthecontrolgroupwas75．00．TherewerewithsignificantdifferencesbetweenthetWOgroups，P<0．05．The1evelsofTG，TC，LDL-CandHDL—Cwerewithoutsignificantdifferencesbeforetreat—ment，P>0．05．8weeksaftertreat

7、ment，thelevelsofTG，TC，LDL-Cweresignificantlylowerthanthecontrolgroup，HDL—Clevelwassignificantlyhigherthanthecontrolgroup，P<0．05．Theincidenceofadversereactionsinthetreat—mentgroupwas5．77，whichwassignificantlylowerthanthecontrolgroup，theincidenceofadversereactionsinpa—tients

8、was11．54，P<0．05．ConclusionTheeffectofatorvastatinintreatmentofcoronaryheartdiseasewithhyp