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1、尤瑞克林治療輕中度急性腦梗死臨床療效觀察[摘要]目的:探討尤瑞克林對輕、中度急性腦梗死的臨床效用。方法:將40例輕、中度急性腦梗死的患者隨機(jī)分為治療組和對照組。治療組20例采用尤瑞克林治療。對照組20例米用丹參治療。對治療前、后進(jìn)行臨床神經(jīng)功能缺損程度的評定和療效評分。測定治療前、后平均血流速度(V)、平均血流量(Q)和外周血管阻力(R),全血黏度、血小板聚集率、紅細(xì)胞壓積。結(jié)果:治療組有效率明顯高于對照組(PV0.05)。治療組用藥后2周與用藥前比較,治療組與對照組治療后比較:平均血流速度(V)和平均血流量(Q)均明顯增加(P<0.05
2、),外周血管阻力(R)均明顯降低(PV0.05);用藥后2周,治療組和對照組全血高切、低切黏度和血小板聚集率、紅細(xì)胞壓積均無顯著性差異(P>0.05)。結(jié)論:尤瑞克林治療輕、中度急性腦梗死安全有效。[關(guān)鍵詞]輕、中度急性腦梗死;尤瑞克林;臨床療效[中圖分類號]R743.33[文獻(xiàn)標(biāo)識碼]B[文章編號]1673-7210(2010)11(c)-034-03ClinicalcurativeeffectobservationonHumanUrinaryKallidinogenaseintreatmentoflightly,themoderatea
3、cutecerebralinfarctionLIUYuting,CHENXiaofei(DepartmentofNeurology,ShanxiCardiovascularHospital,Taiyuan030024,China)[Abstact]Objective:ToobserveclinicalcurativeeffectofHumanUrinaryKallidinogenasetreatslightly,themoderateacutecerebralinfarction.Methods:40exampleslight,themod
4、erateacutecerebralinfarctionpatientweredividedintothetreatmentgroupandthecontrolgroup,randomly.Thetreatmentgroup(n二20)weretreatedwithHumanUrinaryKallidinogenase,thecontrolgroup(n二20)werewithSalviamiltiorrhiza?Beforeandaftertreatment,evaluatedtheclinicalnervefunctiondamaged
5、egreetheionandcurativeeffectgrading.Determinateaveragebloodstreamspeed(V),theaveragebloodstreammeasures(Q)andcircumferencebloodvesselresistance(R),thewholebloodviscosity,thebloodplateletaccumulationrate,theredbloodcellpressestheproductbeforeandafterthetreatment?Results:Tre
6、atmentgroupeffectivenesswashigherthanthecontrolgroupobviously(P<0.05).Beforethemedicationcomparedwithafterthemedication:thetreatmentgroupapplieddrugslater2weekandbeforethemedicationwerecompared,afterthetreatmentgroupandthecontrolgroupwerecompared:averagebloodstreamspeed(V)
7、andtheaveragebloodstreammeasure(Q)increasedobviously(P<0.05),circumferencebloodvesselresistance(R)reducedobviously(P<0.05);thetreatmentgroupandthecontrolgroupapplieddrugslater2weekwholebloodviscosity(higherandlower)andthebloodplateletaccumulationrate,theredbloodcellpressur
8、eaccumulateswerenotremarkablechanges(P>0.05),non-statisticsdifference?Conclusion:HumanUri