順爾寧對(duì)兒童支氣管哮喘患者療效影響及安全性臨床研究.pdf

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1、第加卷第9期河北醫(yī)學(xué)Voi．2O．No．92014年9月HEBEIMEDICINESep．，2014文章編號(hào)：1006-6233(2014)09—1409-03順爾寧對(duì)兒童支氣管哮喘患者療效影響及安全性臨床研究易英(四川省八一康復(fù)中心兒童康復(fù)科，四川南充611135)摘要：目的：探討順爾寧治療兒童支氣管哮喘的臨床療效和安全性。方法：67例兒童支氣管哮喘隨機(jī)分為觀察組和對(duì)照組，對(duì)照組33例采用常規(guī)基礎(chǔ)治療，觀察組34例常規(guī)基礎(chǔ)治療上加用順爾寧4-5rag／次，1次／d，睡前服用，連續(xù)用藥3個(gè)月。并對(duì)所有患兒隨訪6個(gè)月。結(jié)果：治

2、療后觀察組臨床總有效率為97．06％，高于對(duì)照組的78．79％，差異有統(tǒng)計(jì)學(xué)意義(P

3、．2014．09．001SafetyandEficacyofSingulaironChildrenthBronchialAsthmaY／Ying(Children"sRehabilitation-Eighty—oneRehabilitationCenter-SichuanNanchong611135．China)．Abstract：Objective：Toexploretheclinicalcurativeefectandsafetyofsingulairintr．eatmentof67casesbronchialasthm

4、ainchildren．Method：67casesofbronchialasthmainchildrenwererandomlydividedintoobservationgroupandcontrolgroup。33casesincontrolgroupweretreatedwithconventionalfounda-tion-34casesinobservationgroupweretreatedwithsingulairbasedonconventionalfoundation，4to5rag／times-oned

5、ay，beforesleeping，continuoususedfor3months．Allofthechildrenwerefollowedupfor6months．Result：AftertreatmentItheclinicalefectiveratewasinobservationgroup(97．06％)，whichwashigherthanincontrolgroup(78．79％)，thediferenceWasstatisticallysignificant{P<0．05)；Thedisappeartimeo

6、fbreathing-breathingdifficultyandwheezinginobservationgroupWaSshorterthanthoseincontrolgroup-thediferencewasstatisticallysignifcant(P<0．05)；followedupfor6months，recurrenceratewas5．88％inobservationgroup-whichWaslowerthanthecontrolgroup，thediferencewasstatisticallysi

7、gnifcant(P<0．05)：Allpatientswerewithoutobviouadversereaction．Conclusion：Theclinicalcurativeefectofsingulairintreatmentofbronchialasthmainchildrenisverygood。itcanefectivelyimprovetheclinicalsymp—toms，reducetherecurrencerate，whichisasafetreatmentmethod．Keywords：Singu

8、lair；Bronchialasthmainchildren；Clinicalcurativeefect·基金項(xiàng)目：國(guó)家科技支撐計(jì)劃課題。(編號(hào)：2012BAI34B02)·1409·第2O卷第9期河北醫(yī)學(xué)Vo1．20，No．92014年9月HEBEIMEDICINESep．，2014支氣