資源描述:
《右美托咪定對(duì)腰硬聯(lián)合麻醉下手術(shù)病人鎮(zhèn)靜效果分析.pdf》由會(huì)員上傳分享,免費(fèi)在線閱讀,更多相關(guān)內(nèi)容在行業(yè)資料-天天文庫(kù)。
1、現(xiàn)代生物醫(yī)學(xué)進(jìn)展www.shengwuyixue.comProgressinModemBiome~cmeVoL13NO20JUL2013·3857·右美托咪定對(duì)腰硬聯(lián)合麻醉下手術(shù)病人鎮(zhèn)靜效果分析術(shù)王彥強(qiáng)羅遠(yuǎn)國(guó)李洪陸捷馬寬生△(1解放軍第181醫(yī)院麻醉科廣西桂林541002;2第三軍醫(yī)大學(xué)西南醫(yī)院肝膽外科重慶400038)摘要目的:探究右美托咪定對(duì)腰硬聯(lián)合麻醉下手術(shù)病人鎮(zhèn)靜效果。方法:選取我院于2008年9月-2011年4月收治的腰硬聯(lián)合麻醉下手術(shù)患者160例,按照隨機(jī)數(shù)字表平均分為觀察組及對(duì)照組,各80例,分別在麻醉后注射右美托咪定
2、及生理鹽水,觀察兩組患者BIS、Ramsay、心率等鎮(zhèn)靜指標(biāo),并觀測(cè)血流動(dòng)力學(xué)變化,探討右美托咪定的鎮(zhèn)靜效果及安全性。結(jié)果:觀察組BIS術(shù)前與術(shù)中BIS指數(shù)分別為93.8±4.9及65.2±3.6,Ramsay評(píng)分分別為2.1±0.5及4.0±0.8,心率分別為71.5±5.8及60.7±4.2,上述三項(xiàng)指標(biāo)術(shù)中與術(shù)前數(shù)據(jù)存在明顯統(tǒng)計(jì)學(xué)差異,且與對(duì)照組同一時(shí)期對(duì)比存在統(tǒng)計(jì)學(xué)差異,血壓指標(biāo)兩組組間及術(shù)前、術(shù)中對(duì)比均不存在統(tǒng)計(jì)學(xué)差異;觀察組出現(xiàn)6例心動(dòng)過緩,5例低血壓,并發(fā)癥發(fā)生率13.8%,對(duì)照組出現(xiàn)5例心動(dòng)過緩,5例低血壓,并發(fā)癥發(fā)
3、生率12.5%,兩組患者并發(fā)癥情況對(duì)比無(wú)明顯統(tǒng)計(jì)學(xué)差異。結(jié)論:右美托嘧啶能夠有效改善腰硬聯(lián)合麻醉手術(shù)患者的BIS指標(biāo)、Ramsay得分及心率情況,能夠阻滯痛覺的傳導(dǎo)、降低心率,從而起到鎮(zhèn)靜、止痛作用,且不會(huì)帶來(lái)更多的麻醉應(yīng)激反應(yīng),效果及安全性均有良好的保障,值得臨床推廣。關(guān)鍵詞:右美托咪定;鎮(zhèn)靜;效果;腰硬聯(lián)合麻醉中圖分類號(hào):R614文獻(xiàn)標(biāo)識(shí)碼:A文章編號(hào):1673-6273(2013)20·3857—03DexmedetomidineSedationEffectofCombinedSpinal—epiduralAnesthesia
4、forPatientsUndergoingOperationunderAnalysis冰WANGYan-jiang,LUOYuan-guo~,LIHong~,LUJi#,MAKuan-shen(1DepartmentofAnesthesioligy,181HospitalofPLA,Guilin,Guangxi,541002;2HepatobiliarySurgery,SouthwestHospital,ThirdMilitaryMedicalUniversity,Chongqing,400038,China)ABSTRACTObj
5、ective:Toexploretheefectsofdexmedetomidineoncombinedspinal—epiduralanesthesiasedationinpatientsunderoperation.Methods:InourhospitalbetweenSeptember2008andApril2011,160patientswhogotcombinedspinal—epiduralanesthesiabeforeoperationwererandomlyandequallydividedintoobserva
6、tiongroupandcontrolgroup.Afterinjectionwithanesthesia,thetwogroupswererespectivelygivendexmedetomidineandphysiologicalsaline,andwereobservedwithBIS,Ramsay,heartrateandothersedativeindex.Thehemodynamicchangeswerealsoobservedandtheeficacyandsafetyofsedationwithdexmedetom
7、idinewereinvestigatedaswel1.Results:Intheobservationgroup,thepreoperativeandintraoperativeBISindexwere93.8±4.9and65.2±3.6,Ramsayscoreswere2.1±0.5and4±0.8,heartratewere71.5±5.8and60.7±4.2,respectively.Therewerestatisticallysignificantdiferencesbetweenthepreoperativeandi
8、ntraoperativedataintheabovethreeindexes.Ascomparedwiththedatainthesameperiod,therealsowasstatisticallysignificantdife