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《PET／CT對(duì)TACE聯(lián)合RFA治療原發(fā)性肝癌的療效評(píng)價(jià)-論文.pdf》由會(huì)員上傳分享，免費(fèi)在線閱讀，更多相關(guān)內(nèi)容在應(yīng)用文檔-天天文庫。
1、·34·醫(yī)刊2013年11月第40卷第22期ChineseJournalofPracticalMedicineNov．2013．Vol_40．No．22PET／CT對(duì)TACE聯(lián)合RFA治療原發(fā)性肝癌的療效評(píng)價(jià)蔡越飛鐘勝冼重楊譚小明賈志斌高中山【摘要】目的探討PET／CT在經(jīng)動(dòng)脈導(dǎo)管栓塞化療(TACE)聯(lián)合射頻消融(RFA)治療原發(fā)性肝癌后的應(yīng)用價(jià)值。方法本組21例原發(fā)性肝癌患者共有31個(gè)病變，腫瘤最大徑為1．0—12．5cm。其中15例為初治病例，6例為肝癌手術(shù)后復(fù)發(fā)。經(jīng)過TACE聯(lián)合RFA治療后3周，對(duì)比CT和PET／CT檢查的結(jié)果。如發(fā)現(xiàn)有腫瘤殘留，在1周內(nèi)
2、對(duì)其再次行RFA治療。結(jié)果21例患者經(jīng)一次TACE聯(lián)合一次RFA治療3周，經(jīng)病變區(qū)域活檢及數(shù)字減影血管造影等檢查發(fā)現(xiàn)19例有部分腫瘤殘留，腫瘤殘留最大徑為0．5～3．5cm。cT增強(qiáng)掃描檢查檢出10例，檢出率為52．6％；PET／CT檢出有17例殘留，檢出率為89．5％。根據(jù)PET／CT檢查結(jié)果，在1周內(nèi)再次行RFA治療，PET／CT檢查發(fā)現(xiàn)16例患者腫瘤無殘留，1例患者3周后復(fù)查PET／CT發(fā)現(xiàn)肝內(nèi)病變未完全控制，行第3次RFA。結(jié)論原發(fā)性肝癌經(jīng)TACE聯(lián)合RFA治療后，PET／CT對(duì)判斷腫瘤殘留以及指導(dǎo)進(jìn)一步RFA治療較CT檢查具有更大的優(yōu)勢?！娟P(guān)鍵詞】原發(fā)
3、性肝癌；射頻消融；經(jīng)動(dòng)脈導(dǎo)管栓塞化療；PET／CTEficacyevaluationoftranscatheterarterialchemo-embolizationcombinedwithradiofrequencyablationonpatientswithhepatocellularcarcinomabyPET／CTCAIYue，ZHONGSheng，XIANChong—yang，TANXiao—ming，JlAzhi—bin，GAOZhong—shan．DepartmentofInterventionalRadiol—ogy，DonghuaHospita
4、lofDongguan，Dongguan523110，China【Abstract】ObjectiveToinvestigatethevalueofPEI1／cTinjudgingtumorresidueofhepato—cellularcarcinoma(HCC)aftertreatedbytranscatheterarterialchemo—embolization(TACE)combinedwithradiofrequencyablation(RFA)．MethodsTwentyoneHCCpatientswith31lesions，1．0—12．5cmi
5、ndiameter．weretreatedinourhospitalfromDecember2009toDeeember2011．0fthe21patients．15caseswerenaivepatientswith21lesions，6patientswererelapsedafterhepatectomy．TheresultsofCTandPET／CTofthe21patients3weeksaftertreatmentofTACEcombinedwithRFAwerecompared．Iftumorresiduewasdictated，afurtherR
6、FAtreatmentwouldbeappliedwithinoneweek．ResultsOfthe21HCCpatientsthatreceivedonecourseofTACEcombinedwithRFA，19caseshadtumorresidueswhichwereconformedbyfineneedlebiopsyanddigitalsubstractionangiography(DSA)．CTonlydetec—ted10positivecases；however，PET／CTdetected17positivecases．Positivera
7、teofCTwas52．6％，andthatofPET／CTwas89．5％．AccordingtotheresultsofPET／CTofthe17patients．a(chǎn)fterthesecondcourseofRFA．16patientshadriotumorresidue。lcasesurvivedwithuncontrolledlesions3weeksaftertreatment．ConclusionsPET／CTisbetterthanCTiniudgingtumorresidueofHCCaftertreatmentofTACEcombinedwit
8、hRFA．a(chǎn)ndingu
