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1、·l76·中國臨床醫(yī)學(xué)影像雜志2014年第25卷第3期JChinClinMedImaging，2014，Vo1．25，No．3實(shí)時(shí)超聲彈性成像評價(jià)肝臟射頻消融灶的價(jià)值彭金波，楊紅，何云，覃肖溪(廣西醫(yī)科大學(xué)第一附屬醫(yī)院超聲科，廣西南寧530021)【摘要1目的：利用實(shí)時(shí)超聲彈性成像(Real—timeelastography，RTE)觀察離體及活體肝臟射頻消融(Radiofrequencyabla．tion，RFA)術(shù)后消融灶的彈性變化，探討RTE評估RFA消融范圍的價(jià)值。方法：離體實(shí)驗(yàn)選取新鮮離體豬肝5個(gè)，活體實(shí)驗(yàn)選取新西蘭大
2、白兔2O只。在超聲引導(dǎo)下將射頻針置于豬肝及兔肝內(nèi)進(jìn)行消融，分別得到消融灶20個(gè)。RFA結(jié)束后采用RTE觀察消融灶，測量消融灶最大切面的左右徑及前后徑并計(jì)算面積，與大體標(biāo)本測量值進(jìn)行比較。結(jié)果：消融結(jié)束后RTE圖像顯示離體豬肝及活體兔肝消融灶呈均勻藍(lán)色．與周圍組織分界清楚。Pearson相關(guān)分析顯示離體豬肝RFA術(shù)后RTE測量消融灶面積與大體標(biāo)本測量結(jié)果呈顯著相關(guān)(r=0．91，P<0．05)。Spearman相關(guān)分析顯示活體兔肝RFA術(shù)后RTE測量消融灶面積與大體標(biāo)本測量結(jié)果亦具有較好的相關(guān)性(r=0．49，P<0．05)。結(jié)論
3、：RTE可清晰顯示肝臟RFA灶的范圍，有望成為評價(jià)RFA的有效方法?！娟P(guān)鍵詞】肝；兔；豬；導(dǎo)管消融術(shù)；超聲檢查【中圖分類號】R333．4；R445．1【文獻(xiàn)標(biāo)識碼】A[文章編號】1008—1062(2014)03—0176—03Thevalueofreal-timeelastographyinevaluatingtheefectofradiofrequeneyablativetreatmentinliverlesions：anexperimentalstudyPENGJin-bo，YANGHong,HEYun，QmXiao-xi
4、(DepartmentofMedicalUltrasonics，F(xiàn)irstAffiliatedHospital,GuangxiMedicalUniversity,Nanning530021，China)Abstract：Objective：Toinvestigatetheelasticitychangeofablativelesionsresultingfromradiofrequencyablation(RFA)invitroliverandinvivoliverbyreal-timeelastography(RTE)，eva
5、luateRTEindepictingcircumscriptionofablativelesions．MaterialsandMethods：Fiveinvitroporcineliversandtwentyrabbitsliverswerechosenforthisstudy．Twentyablativele—sionswereobtainedusingRFAunderultrasoundguidanceineachexperiment．AfterRFA，RTEwasperformed．Themaximumve~icaldi
6、ameterandtransversediameterofablativelesionsweretakenonRTEimageandcomparedwiththemeasurementsobtainedfrompathologicexamination．Results：HomogeneousblueanddistinctcircumscriptionfromlivertissuewasshowedonRTEimageofallablativelesionsperformedRFAinexperiments．Pearsoncorr
7、elationanalysisdemonstratedthattheareaofablativelesionsmeasuredonRTEimageperformedafterRFAcorrelatedwellwiththemeasurementonmacropathologyspeci—men(r=0．91，P<0．05)invitroliverexperment．AndSpearmancorelationanalysisdemonstratedthattheareaofablativelesionsmeasuredonRTEi
8、mageperformedafterRFAcorrelatedwellwiththemeasurementonmacropathologycorrelatedfr=0．49．P<0．051invivoliverexperment．Conclusions：RTEm
