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1、提要目的:觀察益氣養(yǎng)陰清肝方在治療中醫(yī)辨證屬于陰虛陽亢型Graves病的臨床療效,比較中藥與西藥在消除甲狀腺腫大療效上的差異,以及對患者實驗室相關(guān)指標(biāo)的影響,為臨床使用提供理論依據(jù)。方法:采用隨機(jī)、對照的方法,將60例陰虛陽亢型Graves病患者隨機(jī)分為治療組和對照組,各30例。所有受試者在接受治療時均進(jìn)行基礎(chǔ)治療,治療組在此基礎(chǔ)上加用中藥益氣養(yǎng)陰清肝方進(jìn)行治療,對照組在此基礎(chǔ)上加用他巴唑進(jìn)行治療。觀察時間為8周,主要觀察指標(biāo):臨床癥狀、心率、體重、基礎(chǔ)代謝率、甲狀腺腫、突眼度、甲功、肝功、血常規(guī)等。結(jié)果:治療組治療后臨床癥狀積分、心率、體重、
2、基礎(chǔ)代謝率、甲狀腺腫、突眼度、甲功等較前改善明顯,與對照組比較有顯著性差異。試驗期間未發(fā)現(xiàn)不良反應(yīng)。結(jié)論:益氣養(yǎng)陰清肝方聯(lián)合行為干預(yù)方式對陰虛陽亢型Graves病患者療效顯著,可以明顯改善患者臨床癥狀、心率、體重、基礎(chǔ)代謝率、甲狀腺腫、突眼度、甲功等,且用藥安全,證明了中醫(yī)藥辯證論治的有效性,正確運用中醫(yī)藥辨證施治治療Graves病前景廣闊。關(guān)鍵詞臨床觀察;Graves?。魂幪撽柨盒?;益氣養(yǎng)陰清肝方TheClinicalObservationinTreatingQiandYindeficiencysyndromeofGravesDiseasew
3、ithYiQiYangYinQingGanFangSpecialty:InternalMedicineofTraditionalChineseMedicineAuthor:SunXuminTutor:Pro.XuYunshengAbstractObjective:ObservetheclinicalcurativeeffectionofChinesepatentdrug“YiQiYangYinQingGanFang”intreatingQiandYindeficiencysyndromeofGravesDisease,thedifference
4、effectbetweenChinesemedicineandwesternmedicineinremovingThyromegalyiscompared,andthereeffectsinsomelaboratorydataarealsocompared,Offeringatheoreticalbasisfortheclinicaluse.Methods:Takingthemethodofrandomandantitheses,60patientswithQiandYindeficiencysyndromeofGravesDiseasewer
5、edividedintotreatmentgroup(n=30)andthecontrolgroup(n=30).Alltheparticipantshadreceivedthebasiccure,thetreatmentgroupreceivedthebasiccureplusYiQiYangYinQingGanFang,anothergroupreceivedthebasiccureplustapazole.Observationtimelastfor8weeks,themainoutcomemeasuresareasfollows:the
6、clinicalsymptoms,heartrate,weight,basalmetabolicrate(BMR),thyrocele,protrudingeyesdegrees,thyroidfunction,liverfunction,bloodroutineexaminationandsoon.Results:Aftercured,theclinicalsymptoms,heartrate,weight,BMR,thyrocele,protrudingeyesdegrees,thyroidfunction,liverfunction,bl
7、oodroutineexaminationandsoonwereobviouslyimproved,whichshowedsignificantdifferencefromthecontrolgroup.Duringthetestsadversereactionsdidnotappear.Conclusion:YiQiYangYinQingGanFanghascurativeeffectonQiandYindeficiency,syndromeofGravesDisease,whichcanimprovespatientsclinicalsym
8、ptoms,heartrate,weight,BMR,thyrocele,protrudingeyesdegrees,thyroidfunction,