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1、Mammary-typemyofibroblastoma乳腺型肌纖維母細胞瘤一、Definition定義Abenignmesenchymalneoplasm良性間葉性腫瘤composedofspindle-shapedcellswithfeaturesofmyofibroblasts,由梭形有肌纖維母細胞特征的細胞構(gòu)成的embeddinastromathatcontainscoarsebandsofhyalinizedcollagen間質(zhì)內(nèi)含有玻璃樣變的粗大膠原纖維條帶andconspicuousmastcells可見大量的肥大細胞andadm
2、ixedwithavariableamountofadiposetissue.并伴有數(shù)量不等的脂肪組織。thetumourishistologicallyidentiacaltomyofibroblastomaofbreast.其組織學(xué)特點與乳腺的肌纖維母細胞瘤相似。二、Epidemiology流行病學(xué)Lesionhaveariseninadultswithanagerangeof35to67years(median55.5years)andamalepredilection(8males,2females).發(fā)病年齡見于35-67成年人（平均
3、55.5）男性多見（8例男性，2例女性）Theextrammarylocationofsomemyofibroblastomashasonlyrecentlybeendefinedwhen10caseswerereported.乳腺外的肌纖維母細胞瘤直到最近才有10例報告。Therefore,conclusionsrelatedtoepidemiologycouldalterwithincreasedtumourrecognition因此隨著對腫瘤認(rèn)識的增加，流行病學(xué)方面也會發(fā)生改變。三、sitesofinvolvement受累部位Themos
4、tcommonlocationofmammary-typemyofibroblastomaistheinguinal/groinarea.乳腺型肌纖維母細胞瘤最常見于會陰/腹股溝區(qū)域。Otherreportedsitesincludeabdominalwall，buttock,backandvaginalwall.其他部位有腹壁，臀部，背部和陰道壁。Lesionsarisemostcommonlyinsubcutaneoustissue.最常見的發(fā)病部位是皮下組織。However,caseshavearisendeeptoabdominalwa
5、llmuscle，intheposteriorvaginalwallandinaparatesticularlocation.但也可位于腹壁肌肉，陰道后壁和睪丸旁。Thereisanapparentpredilectionformyofibroblastomastoarisealongtheputativeanatomic“milk-line”thatextendsfromaxillatomedialgroin.肌纖維母細胞瘤明顯好發(fā)于從腋窩至腹股溝中部的“白線”四、Clinicalfeatures臨床特點Thetumoursgenerally
6、presentaseitherpainlessmassesorincidentallesionsthataredetectedduringsurgicalproceduressuchasinguinalherniarepair.多為無痛性的腫塊或由外科進行腹股溝疝修補術(shù)時偶然發(fā)現(xiàn)隱匿腫塊。Occasionallesionsaretenderorpainful偶爾病變區(qū)觸痛或疼痛。Tumourshavebeendescribedtobepresentforuptoayearbeforeclinicalpresentation.腫瘤就診前可能已經(jīng)存
7、在達1年之久Therearenoimagingdata無影像學(xué)資料數(shù)據(jù)五、Aetiology病因?qū)WUnknown病因不明Ithasbeenpostulatedthatmyofibroblastomasarisinginthebreastmayberelatedtoapatient’shormonalstatus,inthatlesionsarerelativelycommoninoldermen.e.g.inthesettingofgynaecomastiaandanti-androgentherapy.據(jù)推測發(fā)生于乳腺的肌纖維母細胞瘤與患者的
8、激素水平有關(guān).這種情況多見于老年男性。如：男性乳腺發(fā)育和抗雄激素治療的患者。Mammary-typemyofibroblastomaofsofttis
