Abdominal Aortic Calcification, BMD, and Bone MicrostructureA Population-Based Study腹主動(dòng)脈鈣化、骨密度、骨的微觀結(jié)構(gòu)： 基于人口的研究

Abdominal Aortic Calcification, BMD, and Bone MicrostructureA Population-Based Study腹主動(dòng)脈鈣化、骨密度、骨的微觀結(jié)構(gòu)： 基于人口的研究

ID：40849645

大小：1007.58 KB

頁(yè)數(shù)：12頁(yè)

時(shí)間：2019-08-08

Abdominal Aortic Calcification, BMD, and Bone MicrostructureA Population-Based Study腹主動(dòng)脈鈣化、骨密度、骨的微觀結(jié)構(gòu)： 基于人口的研究_第1頁(yè)
Abdominal Aortic Calcification, BMD, and Bone MicrostructureA Population-Based Study腹主動(dòng)脈鈣化、骨密度、骨的微觀結(jié)構(gòu)： 基于人口的研究_第2頁(yè)
Abdominal Aortic Calcification, BMD, and Bone MicrostructureA Population-Based Study腹主動(dòng)脈鈣化、骨密度、骨的微觀結(jié)構(gòu)： 基于人口的研究_第3頁(yè)
Abdominal Aortic Calcification, BMD, and Bone MicrostructureA Population-Based Study腹主動(dòng)脈鈣化、骨密度、骨的微觀結(jié)構(gòu)： 基于人口的研究_第4頁(yè)
Abdominal Aortic Calcification, BMD, and Bone MicrostructureA Population-Based Study腹主動(dòng)脈鈣化、骨密度、骨的微觀結(jié)構(gòu)： 基于人口的研究_第5頁(yè)
資源描述：

《Abdominal Aortic Calcification, BMD, and Bone MicrostructureA Population-Based Study腹主動(dòng)脈鈣化、骨密度、骨的微觀結(jié)構(gòu)： 基于人口的研究》由會(huì)員上傳分享，免費(fèi)在線閱讀，更多相關(guān)內(nèi)容在學(xué)術(shù)論文-天天文庫(kù)。

1、JOURNALOFBONEANDMINERALRESEARCHVolume23,Number10,2008PublishedonlineonMay5,2008;doi:10.1359/JBMR.080504?2008AmericanSocietyforBoneandMineralResearchAbdominalAorticCalcification,BMD,andBoneMicrostructure:APopulation-BasedStudy112231JohnTChow,SundeepKhosla,LJosephMeltonIII,ElizabethJAtkinson,JonJCa

2、mp,andAnnEKearnsABSTRACT:Tobetterdefinetherelationshipbetweenvascularcalcificationandbonemass/structure,weassessedabdominalaorticcalcification(AAC),BMD,andbonemicrostructureinanage-stratified,randomsampleof693Rochester,MN,residents.ParticipantsunderwentQCTofthespineandhipandhigh-resolutionpQCT(HR

3、pQCT)oftheradiustodefinevolumetricBMD(vBMD)andmicrostructuralparameters.AACwasquantifiedwiththeAgatstonscoringmethod.Inmen,AACcorrelatedwithlowervertebraltrabecularandfemoralneckvBMD(p<0.001),butnotafterageormultivariable(age,bodymassindex,smokingstatus)adjustment.Separationinto<50and50yrshowedt

4、hispatternonlyintheoldermen.BV/TVandTb.ThinverselycorrelatedwithAACinallmen(p<0.001),andTb.Thremainedsignificantlycorrelatedafterageadjustment(p<0.05).Tb.NpositivelycorrelatedwithAACinyoungermen(p<0.001)butnegativelycorrelatedinoldermen(p<0.001).TheoppositewastruewithTb.Sp(p0.01andp<0.001,respec

5、tively).LowerTb.NandhigherTb.SpcorrelatedwithAACinoldermenevenaftermultivariableadjustment.Amongallwomenandpostmenopausalwomen,AACcorrelatedwithlowervertebralandfemoralneckvBMD(p<0.001)butnotafteradjustment.LowerBV/TVandTb.ThcorrelatedwithAAC(p0.03andp0.04,respectively)inwomen,butnotafteradjust

6、ment.Ourfindingssupportanage-dependentassociationbetweenAACandvBMD.WealsofoundthatAACcorrelateswithspecificbonemicrostructuralparametersinoldermen,suggestingapossiblecommonpathogenesisforvascularcalcificationanddeteriorationinbonestructure.However,sex-specificdifferencesexist.JBoneMinerRes2008;23

7、:1601–1612.PublishedonlineonMay5,2008;doi:10.1359/JBMR.080504Keywords:bonecomposition,boneQCT,osteoporosis,populationstudies,association(23,24,36)INTRODUCTIONwomen.Studiesinvolvingmenhavebeenevenless(9,24,29,30,32,33,3

當(dāng)前文檔最多預(yù)覽五頁(yè)，下載文檔查看全文

此文檔下載收益歸作者所有

當(dāng)前文檔最多預(yù)覽五頁(yè)，下載文檔查看全文
溫馨提示：
1. 部分包含數(shù)學(xué)公式或PPT動(dòng)畫(huà)的文件，查看預(yù)覽時(shí)可能會(huì)顯示錯(cuò)亂或異常，文件下載后無(wú)此問(wèn)題，請(qǐng)放心下載。
2. 本文檔由用戶上傳，版權(quán)歸屬用戶，天天文庫(kù)負(fù)責(zé)整理代發(fā)布。如果您對(duì)本文檔版權(quán)有爭(zhēng)議請(qǐng)及時(shí)聯(lián)系客服。
3. 下載前請(qǐng)仔細(xì)閱讀文檔內(nèi)容，確認(rèn)文檔內(nèi)容符合您的需求后進(jìn)行下載，若出現(xiàn)內(nèi)容與標(biāo)題不符可向本站投訴處理。
4. 下載文檔時(shí)可能由于網(wǎng)絡(luò)波動(dòng)等原因無(wú)法下載或下載錯(cuò)誤，付費(fèi)完成后未能成功下載的用戶請(qǐng)聯(lián)系客服處理。