冠狀病毒Coronavirusl論文-1990 A Serologic Survey of Oklahoma Cats for Antibodies to Feline Immunodeficiency Virus, Coronavirus, and Toxoplasma Go.pdf

冠狀病毒Coronavirusl論文-1990 A Serologic Survey of Oklahoma Cats for Antibodies to Feline Immunodeficiency Virus, Coronavirus, and Toxoplasma Go.pdf

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1、JVetDiagnInvest2:180-183(1990)AserologicsurveyofOklahomacatsforantibodiestofelineimmunodeficiencyvirus,coronavirus,andToxoplasmagondiiandforantigentofelineleukemiavirusSandraJ.Rodgers,CharlesA.BaldwinAbstract.Aserologicsurveywasdoneon618catserasubmittedtotheOklahomaAnimalDi

2、seaseDiagnosticLaboratorybetweenJuly1,1987andJune30,1988.Thesampleswerecollectedfromclinicallynormalandsickcats.Theseraweretestedforthepresenceofantibodiestofelineimmunodeficiencyvirusbyacommercialimmunoassay,toacoronavirusbyanindirectfluorescentantibodytest,andtoToxoplasma

3、gondiibyacom-merciallatexagglutinationtestandforthepresenceoffelineleukemiavirusantigenwithoneof3differentcommercialassaykits.Tenpercentoftheserahadantibodiestofelineimmunodeficiencyvirus,35%hadantibodiestoacoronavirus,and22%hadantibodiestoToxoplasmagondii.Felineleukemiavir

4、usantigenwasdetectedin15%ofthesera.Thirty-twopercentoftheserahadevidenceofexposureto2ormoreoftheagents.l0Felineimmunodeficiencyvirus(FIV),felineinfec-andcaninecoronavirus(CCV).Felineinfectiousperi-tiousperitonitisvirus(FIPV),Toxoplasmagondii,andtonitisviruswasfirstconfirmed

5、intheUnitedStatesl0felineleukemiavirus(FeLV)areinfectiousagentsthatin1963.Onceclinicalsignsdevelop,itisgenerallyacancauseseverehealthproblemsordeathincats.fataldiseaseofbothdomesticandexoticcats.FelineFelineimmunodeficiencyvirusbelongstothefamilyinfectiousperitonitisvirusin

6、fectionoccursprimarily9,11,12Retroviridae,subfamilyLentivirinae.TheFIVvi-incatsthatarebetween6monthsand5yearsofage,ruscausesanimmunosuppressivesyndromeincatswiththehighestincidenceoccurringbetween6monthsl0thatmaymakethecatsusceptibletosecondarypatho-and2years.Thefelinecoron

7、aviruses,FIPVand2,3,8,12,13FECV,aremorphologicallyandantigenicallysimilargensFelineimmunodeficiencyviruswasfirstidentified(andwasoriginallynamedfelineT-lympho-toTGEVandCCV.trophiclentivirus)inearly1987inCaliforniaduringToxoplasmagondii,acoccidialprotozoanparasite,lladisease

8、outbreakinalargecolonyofpetcats.Ainfectsmanyspeciesofmammalsandbirds.Inthelimiteds

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