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1、AcceptedManuscriptPredictingthereceptor-bindingdomainusageofthecoronavirusbasedonkmerfrequencyonspikeproteinZhaozhongZhu,ZhengZhang,WenjunChen,ZenaCai,XingyiGe,HaizhenZhu,TaijiaoJiang,WenjieTan,YousongPengPII:S1567-1348(18)30128-XDOI:doi:10.1016/j.meegid.2018.03.028Reference:MEEGID346
2、3Toappearin:Infection,GeneticsandEvolutionReceiveddate:8March2018Reviseddate:26March2018Accepteddate:28March2018Pleasecitethisarticleas:ZhaozhongZhu,ZhengZhang,WenjunChen,ZenaCai,XingyiGe,HaizhenZhu,TaijiaoJiang,WenjieTan,YousongPeng,Predictingthereceptor-bindingdomainusageofthecorona
3、virusbasedonkmerfrequencyonspikeprotein.Theaddressforthecorrespondingauthorwascapturedasaffiliationforallauthors.Pleasecheckifappropriate.Meegid(2018),doi:10.1016/j.meegid.2018.03.028ThisisaPDFfileofanuneditedmanuscriptthathasbeenacceptedforpublication.Asaservicetoourcustomerswearepro
4、vidingthisearlyversionofthemanuscript.Themanuscriptwillundergocopyediting,typesetting,andreviewoftheresultingproofbeforeitispublishedinitsfinalform.Pleasenotethatduringtheproductionprocesserrorsmaybediscoveredwhichcouldaffectthecontent,andalllegaldisclaimersthatapplytothejournalpertai
5、n.ACCEPTEDMANUSCRIPTPredictingthereceptor-bindingdomainusageofthecoronavirusbasedonkmerfrequencyonspikeprotein1,#1,#111ZhaozhongZhu,ZhengZhang,WenjunChen,ZenaCai,XingyiGe,Haizhen1,23,45,*1,*Zhu,TaijiaoJiang,WenjieTan,YousongPeng1CollegeofBiology,HunanUniversity,Changsha,China2StateKey
6、LaboratoryofChemo/BiosensingandChemometrics,HunanUniversity,Changsha,China3CenterofSystemMedicine,InstituteofBasicMedicalSciences,ChineseAcademyofMedicalSciences&PekingUnionMedicalCollege,Beijing,China4SuzhouInstituteofSystemsMedicine,Suzhou,China5NationalInstituteforViralDiseaseContr
7、olandPrevention,ChinaCDC,Beijing100052,China#TheseauthorscontributedequallytothisworkACCEPTEDMANUSCRIPT*Correspondence:tanwj28@163.com(WT),pys2013@hnu.edu.cn(YP)ACCEPTEDMANUSCRIPTTotheeditor,Thecoronavirusisanenveloped,positive-sense,single-strandedRNAvirus.Itcouldbeclassifiedintofour
8、major