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《咪唑安定聯(lián)合腰硬聯(lián)合麻醉對(duì)婦科手術(shù)患者鎮(zhèn)靜和術(shù)后遺忘效果觀察.pdf》由會(huì)員上傳分享,免費(fèi)在線閱讀,更多相關(guān)內(nèi)容在行業(yè)資料-天天文庫。
1、現(xiàn)代生物醫(yī)學(xué)進(jìn)展www~shengwuyixue.comProgressinModernBiome~cmeVoL13NO.21JUL2013·4155·咪唑安定聯(lián)合腰硬聯(lián)合麻醉對(duì)婦科手術(shù)患者鎮(zhèn)靜和術(shù)后遺忘效果觀察謝銳捷劉少芬張松林房瑞林陳銘君莫堅(jiān)(1普寧市婦幼保健院廣東普寧515300;2廣東醫(yī)學(xué)院附屬第一醫(yī)院廣東廣州524001)摘要目的:本文旨在觀察咪唑安定聯(lián)合腰硬聯(lián)合麻醉對(duì)婦科手術(shù)患者術(shù)后鎮(zhèn)痛遺忘效果。方法:將200例ASAI~I(xiàn)I級(jí)腰硬聯(lián)合麻醉下行婦科手術(shù)患者隨機(jī)分為兩組:咪唑安定組(A組)和對(duì)照組(B組)。兩組患者分別于麻醉前3
2、0分鐘靜脈注射咪唑安定0.1mg/kg和O.9%生理鹽水2mL。觀察用藥前后病人鎮(zhèn)靜情況,鎮(zhèn)靜分級(jí),對(duì)麻醉和手術(shù)操作的遺忘程度和病人的心理狀態(tài)。結(jié)果:根據(jù)Ramsay分級(jí)標(biāo)準(zhǔn)對(duì)患者鎮(zhèn)靜程度進(jìn)行評(píng)判,兩組患者都能維持5分以下鎮(zhèn)靜。A組患者鎮(zhèn)靜程度于切皮后5分鐘、手術(shù)進(jìn)行30分鐘和手術(shù)結(jié)束時(shí)鎮(zhèn)靜程度顯著優(yōu)于B組患者,有統(tǒng)計(jì)學(xué)意義(P<0.05)。兩組患者術(shù)后24小時(shí)內(nèi)隨訪結(jié)果發(fā)現(xiàn):A組患者不產(chǎn)生遺忘、不完全遺忘和完全遺忘人數(shù)分別占總?cè)藬?shù)的0、3%和97%;B組分別為7%、25%和68%。A組與B組比較差異有顯著性(P<0.05),A組順行性遺
3、忘作用優(yōu)于B組。結(jié)論:給予患者術(shù)前30分鐘靜脈注射咪唑安定0.1mg&g有助于提高患者術(shù)中鎮(zhèn)靜程度和術(shù)后遺忘率。故咪唑安定作為婦科手術(shù)麻醉前用藥效果明確可靠。關(guān)鍵詞:婦科手術(shù);腰硬聯(lián)合麻醉;咪唑安定;鎮(zhèn)靜效果;順行性遺忘中圖分類號(hào):R713文獻(xiàn)標(biāo)識(shí)碼:A文章編號(hào):1673·6273(2013)21-4155—04ClinicalObserval:ionofMidazolam’SSedativeEffectandAnterogradeAmnesiaEffectonGynecologicSurgeryPatientsUndergoing一bD
4、?lnal-Epl·d'ura●lA▲nest●nesl0aX/ERui-jie~,L1UShao-fen1,ZHANGSong-lift,FANGRui-lin1,CHENMing-jun~,MOJiane(IPuningmaternalandChildHealthHospital,515300,China;2TheFirstAfSliatedHospitalofGuangzhoumedicaluniversity,524001,China)ABSTRACTObjective:Toexplorethesedativeefectsanda
5、nterogradeamnesiaefectofmidazolamintravenousinjectionusedbe—forecombinedspinal—epiduralanesthesiaoncalmingdownthepatientsandtheirforgettingdegreeofprocedure.Method:200ASAI—IIpatientsscheduledforgynecologicsurgeryunderspinal—epiduralanesthesiawereincludedinthestudy.Patient
6、swererandomlyassignedintotwogroupswith100caseseach.GroupAusedmidazolamwhileGroupBused0.9%sodiumascontro1.GroupAusedmidazolamf0.1mg/kg)asintravenousinjection30minutesbeforeanesthesiawhilegroupBused2ml0.9%sodiumascontro1.Recordandcomparethepatients’sedativeefectbeforeoperat
7、ionbeganandtheforgettingdegree24hoursafteroperationfinished.Result:AccordingtotheRamsaystandard,thepatientsingroupAhavesignificantbettersedativeefectthangroupBsinceoperationstarted(P8、3%.Meanwhile.thetransientglobalamnesiarate,thetransientpartialamnesiarateandtheunforgotenratewer