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《血栓抽吸聯(lián)合替羅非班在急性心肌梗死急診介入治療中的療效觀察》由會(huì)員上傳分享，免費(fèi)在線閱讀，更多相關(guān)內(nèi)容在應(yīng)用文檔-天天文庫(kù)。
1、血栓抽吸聯(lián)合替羅非班在急性心肌梗死急診介入治療中的療效觀察石磊白宏索郢安超(內(nèi)象古烏海市人民醫(yī)院心內(nèi)科內(nèi)象古烏海016000)R的：評(píng)價(jià)血栓抽吸導(dǎo)管聯(lián)合替羅非班在急性ST段抬高心肌梗死(STEMI)介入術(shù)中應(yīng)用療效。方法：選擇2012年3月至2014年10月行急診冠狀動(dòng)脈介入治療(PCI)的急性ST段抬高心肌梗死患者86例，其屮應(yīng)用抽吸導(dǎo)管和替羅非班后行PCI組46例，常規(guī)PCI對(duì)照組40例。觀察2組的造影結(jié)果、術(shù)后效果及安全性。結(jié)果：研究組發(fā)病距血管再通時(shí)間、術(shù)后2小時(shí)ST段回落>50%和心
2、肌酶學(xué)峰值時(shí)間均優(yōu)于對(duì)照組(均P<0.05)；梗死相關(guān)血管(IRA)無(wú)復(fù)流發(fā)生率明顯低于對(duì)照組(P<0.05),左室射血分?jǐn)?shù)(LVEF)及左室舒張末內(nèi)徑(LVEDd)明顯好于對(duì)照組，住院期間主要不良心血管事件(MACE,包括死亡、再梗死、再次靶血管重建)的發(fā)生率少于對(duì)照組，差異有統(tǒng)計(jì)學(xué)意義(P均<0.05)。結(jié)論：血栓抽吸聯(lián)合替羅非班治療急性ST段抬高心肌梗死可減少無(wú)復(fù)流或慢血流發(fā)生，可改善術(shù)后心臟功能，并且不增加血管不良事件的發(fā)生率?！娟P(guān)鍵詞】急性ST段抬高心肌梗死；冠狀動(dòng)脈介入
3、治療；血栓抽吸導(dǎo)管;替羅非班R453A2095-1752(2015)26-0140-02EffectofthrombusaspirationcombinedwithtirofibanduringurgentpercutaneouscoronaryinterventioninpatientswithacutemyocardialinfarctionShiLei,BaiHong,SuoYing,ANChao.(People’sHospital,Wuhai016000,NeiMonggol,C
4、hina)【Abstract】ObjectiveToevaluatetheeffectofthrombusaspirationcombinedwithTirofibanDuringurgentpercutaneouscoronaryintervention(PCI)inpatientswithacutemyocardialinfarction(AMI).MethodsAtotalof86AMIpatientswithurgentPCIwereenrolledfromMarch2012toOctobe
5、r2014.Therewere46patientsreceivedPCIandsuckbycathetercombinedwithTirofiban,another40patientsreceivedroutinePCI.Observethetwogroupsofangiography,postoperatineefficacy,andsafety.ResultsTherewaslowerpeakserumCK-MB,TNIinthestudygroup,comparedwiththecontrol
6、group,ratioofSTsegmentresolution>50%andthecoronaryarteryrecanalizationtimewassignificantlybetter(P<0.05),no-refiowinInfarct-relatedArtery(IRA)afterPCIwaslowerthanthecontrolgroup(P<0.05),leftventriculardiastolicdiameter(LVEDd),leftventricularej
7、ectionfraction(LVEF)andMACEratesinstadygroupweresuperiortothoseinthecontrolgroup(P<0.05).ConclusionApplicationofsuckbycathetercombinedwithtirofibaninpatientswithacutemyocardialinfarctionwaseffective,whichcoulddecreaseno-reflow/slowflowandimprovecard
8、iacfunctionafterPCI.Anddosenotincreasetheincidenceofbloodvesselevent.【Keywords】AcuteST-segmentelevationmyocardialinfarction;Percutaneouscoronaryintervention;Thrombusaspirationcatheter;Tirofiban急性心肌梗死(AMI)是冠狀動(dòng)脈閉塞，血流中斷，使部分心肌因嚴(yán)重的持久性缺血而發(fā)生局部
