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1、動脈介入尿激酶溶栓治療急性腦血栓形成早期的療效觀察瀏陽市集里醫(yī)院神經(jīng)內(nèi)科湖南瀏陽410300【摘要】目的：分析動脈介入尿激酶溶栓治療急性腦血栓形成早期的療效。方法：選取93例急性腦血栓形成早期患者作為研究對象，其中觀察組52例，釆取動脈介入尿激酶溶栓治療；對照組41例，采取尿激酶靜脈溶栓治療；對比兩組患者治療前及治療后2h、6h、24h、72h的歐洲卒中量表(ESS)評分及閉塞血管再通效果。結(jié)果：兩組患者治療后2h、6h、24h、72h的ESS評分均顯著高于治療前水平(P<0.05),似觀察組患者治療后2h、
2、6h、24h、72h的ESS評分均明顯高于對照組，經(jīng)T檢驗，差異具有統(tǒng)計學(xué)意義(P<0.05)；治療前，兩組患者的TT、PT、FIB差異均無統(tǒng)計學(xué)意義(P>0.05)；觀察組閉塞血管完全再通率為59.61%,部分再通率為30.77%,無變化率為9.62%,對照組閉塞血管完全再通率為36.59%,部分再通率為43.90%,無變化率為19.51%;經(jīng)秩和檢驗，觀察組閉塞血管再通效果顯著優(yōu)于對照組，差異具有統(tǒng)計學(xué)意義(P<0.05)。結(jié)論：動脈介入尿激酶溶栓治療急性腦血栓形成早期的療效優(yōu)于靜脈溶栓治療，前者可明顯緩
3、解神經(jīng)功能缺損，對于抑制病情進(jìn)展，改善預(yù)后只有重要作用?！娟P(guān)鍵詞】急性腦血栓；尿激酶；溶栓治療；動脈介入ClinicalobservationoftheearlystageofacutecerebralthrombosistreatedbyinterventionalthrombolysiswithurokinaseYuanLiFengLiuyangshiJilihospitalDepartmentofNeurologyHunanlLiuyang410300[Abstract]Objective：Toanal
4、yzethecurativeeffectoftheearlystageofacutecerebralthrombosistreatedbyinterventionalthrombolysiswithurokinase.Methods：93casesofacutecerebralthrombosispatientsastheresearchobject,theobservationgroupof52cases,takearteryinterventionalthrombolytictherapy；41cases
5、incontrolgroupweretakenintravenousthrombolytictherapywithurokinase；comparedtwogroupsofpatientsbeforeandaftertreatmentof2h,6h,24h，72hoftheEuropeanStrokeScale(ESS)scoreandrecanalizationeffect.Results：twogroupsofpatientsaftertreatmentof2h,6h，24h，72h,ESSscoresw
6、eresignificantlyhigherthanthatbeforetreatment(P<0.05)，butthepatientsintheobservationgroupaftertreatmentof2h,6h，24h,72h,ESSscoresweresignificantlyhigherthanthecontrolgroup，byTtest,thedifferencewasstatisticallysignificant(P<O.O5)beforetreatment,two；grou
7、pTT,PTandFIBshowednosignificantdifference(P>0.05)；observationgroupofocclusivevascularrecanalizationratewas59.61%，partialrecanalizationratewas30.77%,nochangerateis9.62%,thecontrolgroupofvascularocclusionrecanalizationratewas36.59%,partialrecanalizationrat
8、e43.90%,nochangerateis19.51%；therankandinspection,observationgrouprecanalizationeffectwassignificantlybetterthanthecontrolgroup,thedifferencewasstatisticallysignificant(P<0.05).Conclusion：interventi
