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1、動(dòng)脈介入尿激酶溶栓治療急性腦血栓形成早期的療效觀察瀏陽(yáng)市集里醫(yī)院神經(jīng)內(nèi)科湖南瀏陽(yáng)410300【摘要】目的：分析動(dòng)脈介入尿激酶溶栓治療急性腦血栓形成早期的療效。方法：選取93例急性腦血栓形成早期患者作為研究對(duì)象，其中觀察組52例，釆取動(dòng)脈介入尿激酶溶栓治療；對(duì)照組41例，采取尿激酶靜脈溶栓治療；對(duì)比兩組患者治療前及治療后2h、6h、24h、72h的歐洲卒中量表(ESS)評(píng)分及閉塞血管再通效果。結(jié)果：兩組患者治療后2h、6h、24h、72h的ESS評(píng)分均顯著高于治療前水平(P<0.05),似觀察組患者治療后2h、
2、6h、24h、72h的ESS評(píng)分均明顯高于對(duì)照組，經(jīng)T檢驗(yàn)，差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)；治療前，兩組患者的TT、PT、FIB差異均無(wú)統(tǒng)計(jì)學(xué)意義(P>0.05)；觀察組閉塞血管完全再通率為59.61%,部分再通率為30.77%,無(wú)變化率為9.62%,對(duì)照組閉塞血管完全再通率為36.59%,部分再通率為43.90%,無(wú)變化率為19.51%;經(jīng)秩和檢驗(yàn)，觀察組閉塞血管再通效果顯著優(yōu)于對(duì)照組，差異具有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論：動(dòng)脈介入尿激酶溶栓治療急性腦血栓形成早期的療效優(yōu)于靜脈溶栓治療，前者可明顯緩
3、解神經(jīng)功能缺損，對(duì)于抑制病情進(jìn)展，改善預(yù)后只有重要作用?！娟P(guān)鍵詞】急性腦血栓；尿激酶；溶栓治療；動(dòng)脈介入ClinicalobservationoftheearlystageofacutecerebralthrombosistreatedbyinterventionalthrombolysiswithurokinaseYuanLiFengLiuyangshiJilihospitalDepartmentofNeurologyHunanlLiuyang410300[Abstract]Objective：Toanal
4、yzethecurativeeffectoftheearlystageofacutecerebralthrombosistreatedbyinterventionalthrombolysiswithurokinase.Methods：93casesofacutecerebralthrombosispatientsastheresearchobject,theobservationgroupof52cases,takearteryinterventionalthrombolytictherapy；41cases
5、incontrolgroupweretakenintravenousthrombolytictherapywithurokinase；comparedtwogroupsofpatientsbeforeandaftertreatmentof2h,6h,24h，72hoftheEuropeanStrokeScale(ESS)scoreandrecanalizationeffect.Results：twogroupsofpatientsaftertreatmentof2h,6h，24h，72h,ESSscoresw
6、eresignificantlyhigherthanthatbeforetreatment(P<0.05)，butthepatientsintheobservationgroupaftertreatmentof2h,6h，24h,72h,ESSscoresweresignificantlyhigherthanthecontrolgroup，byTtest,thedifferencewasstatisticallysignificant(P<O.O5)beforetreatment,two；grou
7、pTT,PTandFIBshowednosignificantdifference(P>0.05)；observationgroupofocclusivevascularrecanalizationratewas59.61%，partialrecanalizationratewas30.77%,nochangerateis9.62%,thecontrolgroupofvascularocclusionrecanalizationratewas36.59%,partialrecanalizationrat
8、e43.90%,nochangerateis19.51%；therankandinspection,observationgrouprecanalizationeffectwassignificantlybetterthanthecontrolgroup,thedifferencewasstatisticallysignificant(P<0.05).Conclusion：interventi
