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1、廣豆根中黃酮類成分研究【關(guān)鍵詞】廣豆根；黃酮；分離 Abstract：ObjectiveTostudytheconstituentsofSophorasubprostrata.MethodsThepoundsnhematographyandtheirstructuresethods.ResultsSixpounds,tonkinensisol(1),lupipferol(4),genistein(5),(L)-maackiain(6),S.subprostrataChenforthefirsttime. Keyg），2（15mg），3（8mg），4（20mg），5（15mg），6（25
2、0mg）?！ ?結(jié)果 3.1化合物1黃色針狀晶體(CHC13)。ESI-MSm/z419［M-H］-；1HNMR(CDCl3,500MHz)δ:6.74(1H,d,J=10.0Hz,H-6),5.66(1H,d,J=10.0Hz,H-7),8.15(1H,d,J=8.8Hz,H-2，6＇),6.98(1H,d,J=8.8Hz,H-3＇,5＇),3.52(2H,d,J=8.0Hz,H-1＂),5.21(1H,t,J=8.0Hz,H-2＂),1.69(3H,s,H-4＂),1.83(3H,s,H-5＂),1.47(3H,s,H-1＇＇＇),1.47(3H,s,H-2＇＇＇),6.60(1H,
3、brs,3-OH),5.77(1H,brs,4＇-OH),11.94(1H,brs,5-OH);13CNMR(CDCl3,500MHz)δ:73.7(C-2),145.4(C-2),135.4(C-3),175.5(C-4),103.6(C-4a),153.0(C-5),104.9(C-5a),115.7(C-6),128.1(C-7),77.9(C-8),157.0(C-9a),107.7(C-10),153.6(C-10a),123.8(C-1＇),129.6(C-2＇),115.7(C-3＇),157.4(C-4＇),115.7(C-5＇),129.6(C-6＇),21.5(C-1＂
4、),122.3(C-2＂),131.7(C-3＂),25.7(C-4＂),18.1(C-5＂),28.3(C-1＇＇＇),28.3(C-2＇＇＇)。經(jīng)查閱文獻(xiàn)，該化合物的波譜數(shù)據(jù)與文獻(xiàn)［3］相符，確定1為越南槐醇。 3.2化合物2黃色晶體（丙酮）。ESI-MSm/z337［M-H］-；1HNMR(Acetone-d6,500MHz)δ:8.26(1H,s,H-2),6.36(1H,s,H-6),7.47(2H,d,J=8.7Hz,H-2＇,6＇),6.90(2H,d,J=8.7Hz,H-3＇,5＇),3.44(2H,d,J=7.2Hz,H-1＂),5.25(1H,t,J=6.7Hz,H-
5、2＂),1.80(3H,s,H-4＂),1.65(3H,s,H-5＂),12.96(1H,s,5-OH)；13CNMR(Acetone-d6,500MHz)δ:154.4(C-2),123.8(C-3),182.1(C-4),161.6(C-5),99.5(C-6),162.4(C-7),107.3(C-8),156.4(C-9),106.3(C-10),123.2(C-1＇),131.2(C-2＇,6＇),116.1(C-3＇,5＇),158.5(C-4),22.1(C-1＂),123.3(C-2＂),132.1(C-3＂),17.9(C-4＂),25.9(C-5＂)。以上數(shù)據(jù)與文獻(xiàn)［4
6、］報道一致，確定2為lupi/z337［M-H］-；1HNMR(Acetone-d6,500MHz)δ:8.13(1H,s,H-2),13.31(1H,s,5-OH),6.49(1H,s,H-8),7.44(2H,d,J=8.0Hz,H-2＇,6＇),6.89(2H,d,J=8.0Hz,H-3＇,5＇)，3.38(2H,d,J=8.0Hz,H-1＂),5.27(1H,t,J=6.7Hz,H-2＂),1.76(3H,s,H-4＂),1.64(3H,s,H-5＂)；13MR(Acetone-d6,500MHz)δ:153.9（C-2）,123.1(C-3),181.6(C-4),160.6(C
7、-5),112.4(C-6),162.6(C-7),93.7(C-8）,156.8(C-9),105.9(C-10),123.9(C-1＇),131.1（C-2＇,6＇）,115.9（C-3＇,5＇）,158.3(C-4＇),21.9(C-1＂),123.1（C-2＂）,131.6(C-3＂),17.8(C-4＂),25.8(C-5＂)。經(jīng)查閱文獻(xiàn)，以上數(shù)據(jù)與文獻(xiàn)［5］相符，確定3為/z353［M-H］-；1HNMR(A
