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1、MetastaticBreastcancerCaseReportGeneralinformationName:WUChunHongAge:40ySex:FemaleDateofadmission:February9th,2011Dateofdischarge:April23th,2011ChiefcomplaintShegothypoesthesiaoflowerlimbsandinabilitytowalkformorethanamonthHistoryofpresentillnessThepatientfeltpaino
2、nthebackbynoobviousincentivesinJune2010Thepainwastingling,especiallyinnight-timeThepatienttookorallytraditionalChinesemedicine,buthadnottangibleeffectsPast,Personal&FamilyHistoryNohepatitis,hypertension,ordiabetesNosmoking,alcoholordrugabuseNoinheriteddiseasesNohis
3、toryofdrugallergyNormalmenstruationClinicalfindingsTheleftbreastpresentedwithdiffusederythemaandedema,indurationaboutsizeof3.0cm*3.0cmUltrasoundexaminationa3cmleftbreastmassandanormalrightbreastThoracicMRIexaminationThoracicMRIexaminationHigh-densitymasswasshownont
4、hesevenththoracic,andbonedestructionalsohadbeenfound.EnhancedMRILaboratoryexamination2011-02-091.HepaticfunctionsALT40U/LAST20U/LTBNormal3.TumormarkersCA19-9Normal2.BloodroutinetestHb82g/L RBC4.54×1012/L WBC6.1×109/LPLT201×109/LpuncturebiopsyShereceivedultrasoundgu
5、idedbreastcoreneedlepuncturebiopsyPuncturetissuepathology:TheleftbreastinvasiveductalcarcinomaPrimarydiagnosisBreastcancerwithbonemetastasisTreatmentOnFebruary11,2011inorthopedicdepartment,ThePatientreceived"thesevenththoracictumorresectionandpediclescrewfixation"H
6、istologicalexaminationSevenththoracictumorswasidentifiedasmetastaticcarcinoma,andtheimmunohistochemistryresultsshowedthepossibilityofbreastcancerbonemetastasiswasverylargeIMMUNOHISTOCHEMICALresultsER++PR++CerbB2-CK20-EMA++,Ckpan+++,CK5/6-TreatmentThepatientrecovere
7、dwell,andthentransferredintoourdepartmentChemotherapytwotimesbeforeoperation:February23,2011March20,2011ThechemotherapyplanwasTECTreatmentAfterthechemotherapyThelesionsareaofleftbreastshowednoreductionTreatmentModifiedradicalmastectomyonmarch31,2011Bilateraloophore
8、ctomyOnthesamedayHistologicalexaminationTheleftbreastinvasiveductalcarcinomaThebasalresectionmarginoftumorwasclosetothesurroundingnormaltissueThe
