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1、安徽醫(yī)科大學(xué)碩士學(xué)位論文TheExperientmentalStudyofPromotiveEffectoftheInlayTri..focusDistractionOsteogenesisinMandibleDefectAbstractMandibulardefectisthecommonesttypeofthehardtissuedefectsintheoralandmaxillofacialdomains.Theimplantofprosthesisandthetransplantationofvariantorautoge
2、nousbonewerethetraditionaryreconstructionmethods.Howevegthesemethodsallhavesomedeficiencyinevitably.Distractionosteogenesis(DO)isanewtechnicinsurgery.Atfirst,itwasusedinlongbonedefects.In1992,McCarthyusedthismethodinoralandmaxillofacialdefects.Thetechnichadagreatdevel
3、opmentinthereconstructionofthemandibulardefects.Butitalsohassomeshortcomingssuchlikethepoorbonequality,longtherapeutictimeandgreatpathy.Asthedevelopmentofthefunctionalitysurgeryandthehi曲lifequalityrequest,theDOspeed,thebonequalityandthedesignofthemachineneedmoreimprov
4、ement.Theinlaytri—focusdistractionosteogenesisisinprogressinDOexceptoutsideinfluentialfactors.ThecharacteristicoftheDOspeed,shortedtherapeutictimeandtheinlaydesignmakesthepatients’lifequalityhi曲.Objective1.Weinvestigatedanddesignedthedistractorinexvivoandestimateditsp
5、ossibility.2.Toestablishanefficientinlaytri—focusdistractionosteogenesis(D0)modeltoconfirmthismethodquicklyandexcellent.Andprepareforthefurtherstudy.4安徽醫(yī)科大學(xué)碩士學(xué)位論文Methods1.Designmentoftheinlaytri—focusdistractorinexvivoWedesignedthedistractor嬲theinternationalDOstandard
6、tochoosethedistractor’Saxle.Thedistractorhastwotransportdiscsandbi—spiralmarkinginaxle.Whenyourevolvetheaxle,thetwodiscsmakethesamedistance.2。Toestablishanefficientinlaytri-focusdistractionosteogenesis(DO)modelThestudygroupdesignedtheinlaytri-focusdistractorandelabora
7、tedbythestandardofinternational.Theprocessusedthebilateralmandiblesself-comparisonmethodontheordinaryexperimentgoat.Aftertheconsolidationperiod,thegoatsbilateralmandiblesweretakentoundergoX-rayimageology,microanatomydetection,scleroustissueslice,electronmicroscopescan
8、ning,achromycinfluorescentlabelingandbonedensitometry.Results1.ThedistractorcoherecompactandwasoperatedsimplyfollowedLilizar