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1、分類號：R651密級：UDC：610學校代碼：11065碩士專業(yè)學位論文血清D-二聚體水平與高血壓腦出血術后預后的判斷何召峰指導教師豐育功教授學位類別臨床醫(yī)學碩士專業(yè)領域神經外科答辯日期2015年5月26日2015年4月13日摘要目的：分析血清D-二聚體水平與高血壓腦出血不同方式手術后預后的關系。方法：選取我院在2013年8月~2014年5月收治的高血壓腦出血患者30例，依照手術方式不同分為微創(chuàng)引流組和開顱血腫清除組，檢測不同時間患者血漿D-二聚體含量，比較相同病人和不同手術病人D-二聚體含量差異，分析預后情況。結果：開顱血腫清除手術和微創(chuàng)引流手術前后的D-二聚體動態(tài)變化存在明
2、顯的差異，P<0.05，微創(chuàng)組D-二聚體的動態(tài)變化低于開顱血腫清除組，P<0.05，微創(chuàng)引流組D-二聚體異常率明顯小于開顱血腫清除組，P<0.05。結論：高血壓腦出血的患者血清D-二聚體水平的變化與患者的治療方法相關性顯著，并與患者的預后存在關系。關鍵詞：D-二聚體；高血壓腦出血；手術；預后AbstractSerumD-dimerlevelsandhypertensiveintracerebralhemorrhageaftersurgeryprognosisObjective:ToanalyzeserumD-dimerlevelsandprognosisofhypertensi
3、veintracerebralhemorrhageaftersurgeryrelationshipsindifferentways.Methods:AhospitalinhypertensivecerebralhemorrhageinAugust2013-May201430casesweretreatedinaccordancewiththeminimallyinvasivesurgicaldrainageweredividedintogroupsandhematomaevacuationgroupdetectedinplasmaD-twodifferentpatientsme
4、rcontent,thesamepatientsandcomparedifferentsurgicalpatientsD-dimerdifferenceanalysisprognosis.Results:hematomaevacuationobviousdifferencesD-dimerdynamicchangesurgeryandminimallyinvasivesurgerybeforeandafterdrainage,P<0.05,thedynamicchangesoftheminimallyinvasivegroupD-dimerbelowhematomaevacua
5、tiongroup,P<0.05,D-dimerminimallyabnormaldrainagegroupwassignificantlylessthanhematomaevacuationgroup,P<0.05.Conclusion:HypertensiveintracerebralhemorrhageinpatientswithserumD-dimerlevelsinpatientswithtreatment-relatedchangessignificantly,andthereisarelationshipwiththeprognosis.Keywords:D-di
6、mer;hypertensivecerebralhemorrhage;surgery;Prognosis目錄引言··········································································································1第一章研究對象與研究方法························································31.1研究對象·····················································
7、······························31.2研究方法··················································································31.3評價指標··················································································31.4統(tǒng)計學分析·····························
