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1、萬方數(shù)據(jù)國隧耋生醫(yī)堂盤壺墊!Q生§旦筮21鲞筮2魍!坐』逝坐:§!業(yè)墊!Q:y叢:!!盟Q:蘭[10][11][123[13][14][15]spinalcordinjuryreducesbrainderivedneurotrophicfactorexpressioninrathippecampns[J].Neuro-science,2009。159:936—939.ZhaoChurunei,DengWei,GageFH.Mechanismsandfunctionalimplicationsofadultneurogenes
2、is[J】.Cell,2008,132(4):645—660.BleschA.TnszynskiMH.Transientgrowthfactorde.1iverysustainsregeneratedax帆8afterspinalcordinju-ry[J].JNeurosci,2007,27(39):10535—10545.LaskeC。StranskyE,LeyheT。eta1.Stage一赫pendentBDNFserumconcentrationsinA]zheimer’edisease[J].JNeuralTran
3、sm。2006,113:1217一1224.PengS,GarzonDJ,MarcheseM,eta1.Decreasedbrain—derivedneurotrophicfactordependsonamyloidaggregationstateintransgenicmousemodesofA]zhei·mer’sdisease[J].JNeurosci。2009,29(29):9231—9239.LeyheT,EschweilerGW,StranskyE,eta1.IncreaseofBDNFserumconcentr
4、ationinlithiumtrea-tedpatientswithearlyALzheimer’Sdisease[J].JAlzheimer’SDis,2009,16(3):649—656.NittaA,MurainR,SuzukiN。eta1.Diabeticneu.ropathiesinbrainareinducedbydeficiencyofBDNF[J3.NeurotoxicoITeratol,2002,24:659—701.[16][17][18][19][20]一113一AnisrnanH,MeraliZ。Ha
5、yleyS.Neumtransmitter.pe叩deandcytokineprocessinrelationtodepressivedisorder:comorbiditybetweendepressionandneu靜degerativedisorders[J】.ProgNeurebiol,2008,85(I):1—74.FrotunatoJJ,R6啪GZ,KitschTR,eta1.Acutehal"mineadministrationinducesantidepressive—likeeffectsandincrea
6、seBDNFleviesintherathippoeam·pus[J].ProgNeuropsyehopharmacolBidPsychia-try,2009,33(8):1425—1430.BathKG。kFS.VariantBDNF(Val66Met)impactonbrainatrnctusmandfunction[J].Cosni.tive,AffectiveandBehavioralNeuroacience,2006,6(1):79—85.FordlT,SehnleC,SchmittG。eta1.Associati
7、onofthebrain—derivedneurotrophicfactorVal66Metpoly-morphismwitlIreducedhippocampalinmajordepres-sion[J].ArchGenPsychiatry。2007。64:410—416.GueriniFR,BeghiE,RiboldazziG。eta1.BDNFVai66MetpolymorphismisassociatedWitlIcognitiveimpairementpatientswitlIParkinson’edisease[
8、J】.EurJNeurol,2009。16(11):1240—1245.輕度認(rèn)知功能障礙的研究進展畢莉珠何迎春張如富杭州市中醫(yī)院老年病科,杭州310007中國<2010—02—0l收稿)摘要輕度認(rèn)知功能障礙是近年的研究熱點,是介于正常老化與癡呆之間的過渡狀態(tài)。本文擬從概念演變、診斷流程、臨