資源描述:
《阿奇霉素序貫療法治療小兒支原體肺炎的臨床觀察.doc》由會(huì)員上傳分享,免費(fèi)在線閱讀,更多相關(guān)內(nèi)容在工程資料-天天文庫。
1、阿奇霉素序貫療法治療小兒支原體肺炎的臨床觀察摘要:目的總結(jié)阿奇霉素序貫療法治療小兒支原體肺炎的臨床效果。方法將我院兒科小兒支原體肺炎患者92例納入,隨機(jī)分組。A組患兒臨床用藥方案為持續(xù)靜脈滴注阿奇霉素治療;B組患兒臨床用藥方案為阿奇霉素序貫療法,將兩組患兒治療后的治療效果、臨床癥狀消退時(shí)間、用藥不良現(xiàn)象發(fā)生情況、治療成本進(jìn)行對(duì)比。結(jié)果A、B兩組治療效果差異不顯著P>0.05。臨床癥狀消退時(shí)間、用藥安全性、治療成本方面,B組均優(yōu)于A組,P關(guān)鍵詞:小兒支原體肺炎;臨床治療成果;阿奇霉素Abstract:ObjectiveTosu
2、mmarizetheclinicaleffectofAzithromycinSequentialTherapyintreatmentofchildrenwithmycoplasmapneumonia.Methods92casesofpediatricmycoplasmapneumoniainourhospitalfromFebruary2014toMay2015wereincludedinthestudy」ntheAgroup,theclinicaltreatmentplanforcontinuousintravenousi
3、nfusionofazithromycintreatment;Bgroupofchildrenwithclinicalmedicationforthetreatmentofazithromycin,thetwogroupsofparentsaftertreatmentefficacy,clinicalsymptomssubsidetime,medicationadversephenomenon,treatmentcostswerecompared.ResultsFromthetreatmenteffect,thetotale
4、ffectiverateofBgroupwas95.65%,thetotaleffectiverateofAgroupwas91.30%,thediffereneewasnotsign訐icantP>0.05.Fromtheclinicalsymptomsdisappearedtime.Bgroupsputum,fever,breathing,chestX-rayshadowfadetimewereshorteringroupP0.05。1.2方法所有患兒給予常規(guī)對(duì)癥治療。包括抗感染、排痰、止咳、補(bǔ)充水分、營(yíng)養(yǎng)、吸氧等。A組
5、患兒臨床用藥方案為持續(xù)靜脈滴注阿奇霉素治療,將10mg/kg阿奇霉素(商品名:希舒美;國(guó)藥準(zhǔn)字H10960167)與5%葡萄糖注射液溶解后靜脈滴注,給藥7d。B組患兒臨床用藥方案為阿奇霉素序貫療法,靜滴3d口服4d。將10mg/kg阿奇霉素與5%葡萄糖注射液溶解后靜脈滴注,給藥3d??诜⑵婷顾胤桨笧?0mg,qd,用藥4d。將兩組患兒治療后的治療效果、臨床癥狀消退時(shí)間、用藥不良現(xiàn)象發(fā)生情況進(jìn)行對(duì)比。1.3評(píng)價(jià)指標(biāo)效果判定標(biāo)準(zhǔn)[3-4]:療效佳:經(jīng)治療7d,患兒發(fā)熱、咳嗽、咳痰、喘氣等癥狀消失;X胸片檢查結(jié)果正常。療效一般:
6、經(jīng)治療7d患兒發(fā)熱、咳嗽、咳痰、喘氣等癥狀有所改善;經(jīng)治療lwX胸片檢查結(jié)果好轉(zhuǎn)。療效差:經(jīng)lw以上治療,患兒臨床發(fā)熱、咳嗽、咳痰、喘氣等癥狀與體征及X胸片檢結(jié)果的數(shù)據(jù)均采用SPSS13.0軟件處理,治療效果和用藥不良現(xiàn)象等數(shù)據(jù)均屬于計(jì)數(shù)數(shù)據(jù)采用%表示,行X2檢驗(yàn),癥狀消退時(shí)間屬于計(jì)量資料,用(x±s)表示,用t檢驗(yàn),P0.05,見表1。查結(jié)果均無明顯改變。1?4統(tǒng)計(jì)學(xué)處理本研究2.2癥狀消退時(shí)間比較從臨床癥狀消退時(shí)間來看,B組咳痰、發(fā)熱、喘氣、胸片檢查陰影消退時(shí)間均短于A組,B組明顯優(yōu)于A組P