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1、地佐辛預(yù)防全身麻醉蘇醒期患者躁動(dòng)的臨床觀察段錦玉尚紅梅郭曉雨(陜西省榆林市第四醫(yī)院陜西榆林719000)【摘要】目的:觀察地佐辛預(yù)防全身麻醉蘇醒期患者躁動(dòng)的效果。方法:選取木院收治的78例ASA1或II級(jí)全身麻醉下行擇期腹腔鏡手術(shù)患者為研究對(duì)象,隨機(jī)分為對(duì)照組與地佐辛組,每組39例?;颊呤中g(shù)結(jié)束前30min,地佐辛組靜脈注射地佐辛5mg,對(duì)照組靜脈注射等量的牛理鹽水。觀察兩組患者躁動(dòng)的發(fā)牛情況,患者的呼吸恢復(fù)時(shí)間、睜眼時(shí)間以及拔管時(shí)間以及不良反應(yīng)等。結(jié)果:地佐辛組的躁動(dòng)評(píng)分明顯優(yōu)于對(duì)照組,兩組相比,差異有統(tǒng)計(jì)
2、學(xué)意義(P<0.05)o地佐辛組和對(duì)照組患者的呼吸恢復(fù)時(shí)間、睜眼時(shí)間以及拔管時(shí)間和不良反應(yīng)發(fā)牛率相比,差異無統(tǒng)計(jì)學(xué)意義。結(jié)論:地佐辛可有效預(yù)防全身麻醉蘇醒期躁動(dòng)的發(fā)生,且安全可靠,值得臨床推廣?!娟P(guān)鍵詞】地佐辛;全身麻醉;蘇醒期躁動(dòng)【中圖分類號(hào)1R614.2【文獻(xiàn)標(biāo)識(shí)碼】B【文章編號(hào)11003-5028(2015)6-0479-02ClinicalEffectofDezocineinPreventionofRestlessnessduringAnesthesia[Abstract]Objective:O
3、bservationofclinicaleffectofdezocineinpreventionofrestlessnessduringanesthesia.Methods:78casesofASAIorIIpatientsundergoingelectivegynecologicallaparoscopyundersevofluranegeneralanesthesiawererandomlydividedinto2groupswith39caseseach.GroupDezocinereceiveddez
4、ocine5mg30minbeforetheendofoperation,GroupControlreceivedequalvolumeofnormalsaline.Theoccurreneeofagitationwasobservedduringwaking-upperiod.Agitationscale;fromthewithdrawaltopatientsawaketime;respiratorydepression,nauseaandvomitingdizziness,skinitchingandot
5、herrelatedadversereactionafterextubationwereobserved.Results:IngroupDezocine,patientsemergenceagitationratewassignificantlylowerthanthatingroupControl(P<0.05),respiratorydepression,constipation,itchingandotheradversereactionsbetweenthe2groupshadnosignifican
6、tdifferenee.Conclusion:Receivedivdezocinebeforetheendofoperationcaneffectivelypreventtheoccurreneeofagitationduringwaking-upperiodofsevofluranegeneralanesthesiaaftergynecologicallaparoscopy.【Keywords]Dezocine;Generalanesthesia;Postoperativeagitation全身麻醉蘇醒期患
7、者躁動(dòng)⑴是麻醉蘇醒期的一種不適當(dāng)行為,其具體表現(xiàn)為⑵語無倫次、肢體的無意識(shí)動(dòng)作、哭喊或呻吟、無理性言語、妄想思維等,這些全身麻醉手術(shù)后的躁動(dòng)掙扎、興奮等現(xiàn)象增加了蘇醒期的風(fēng)險(xiǎn)。如果處理不適當(dāng),將危及患者生命。本研究觀察使用地佐辛預(yù)防全身麻醉蘇醒期患者躁動(dòng)的效果,旨在為全身麻醉蘇醒期躁動(dòng)的藥物預(yù)防研究提供理論依據(jù)。1資料與方法1.1研究對(duì)象選取來我院進(jìn)行治療的ASAI或II級(jí)全身麻醉下行擇期腹腔鏡手術(shù)患者78例作為研究對(duì)象。其中男42例,女36例,年齡16?78歲,平均年齡(43.2±9.2)歲,
8、所有患者均無吸毒史、肝腎功能不全、精神病史及麻醉鎮(zhèn)痛藥物使用史。將患者隨機(jī)分為地佐辛組和對(duì)照組,每組39例。其中,地佐辛組平均年齡(42.9±8.9)歲,手術(shù)時(shí)長(133±55)min;對(duì)照組平均年齡(43?6±9.6)歲,手術(shù)時(shí)長(129±57)min。兩組患者在年齡,性別比例與手術(shù)時(shí)長等因素方面基本均衡,差異無顯著性意義(P>0?05)。1