資源描述：
《替米沙坦對(duì)原發(fā)性高血壓患者動(dòng)脈彈性的影響》由會(huì)員上傳分享，免費(fèi)在線閱讀，更多相關(guān)內(nèi)容在學(xué)術(shù)論文-天天文庫(kù)。
1、olanzapinetreatedschizophreniapatients:adouble-blindwithShuxueningversusclozapineinthetreatmentofnegativeplacebocontrolledstudy[J].Psychopharmacology,2007,symptomofchronicschizophreniapatients[J].SichuanMent192(3):441-448.Health(四川精神衛(wèi)生),2004,17(2):42-43.[13]
2、WANGHQ,XUBJ,MAYC,etal.Theefficacyof[16]ZHAOJP,YANGDS,LIUZN,etal.AlongitudinalstudyShuxueningcombinedwithatypicalantipsychoticsintheofcognitivefunctionandregionalcerebralbloodflowintreatmentofchronicschizophrenia:clinicalobservationof34negativeschizophrenia[J
3、].ChinJPsychiatry(中華精神科雜cases[J].ZhejiangJTraditChinMed(浙江中醫(yī)雜志),2009,志),2000,33(3):134-137.44(9):648-649.[17]NGB,POSTLETHWAITA,ROLLNIKJ.Peripheraloedema[14]LUOHC,SHENGYC,MENGFQ,etal.Therapeuticeffectinpatientstakingolanzapine[J].IntClinPsychopharmacol,ofShux
4、ueningcombiningneurolepticsforthetreatmentof2003,18(1):57-59.chronicschizophrenia?adoubleblindstudy[J].ChinJIntegr[18]STAHLSM.AntipsychoticAgentsEssentialPsychophar-TraditChinWestMed(中國(guó)中西醫(yī)結(jié)合雜志),1997,17(3):macology[M].2nded.Cambridge:CambridgeUniversity139-14
5、2.Press,2000:401-458.[15]JILY,XUZL.Acomparativestudyofclozapinecombined收稿日期：2011-12-16替米沙坦對(duì)原發(fā)性高血壓患者動(dòng)脈彈性的影響*黃漢輝，鄭師明，梅崢嶸，嚴(yán)鵬科(廣州醫(yī)學(xué)院第三附屬醫(yī)院藥學(xué)部，廣州510150)摘要：目的研究替米沙坦對(duì)原發(fā)性高血壓患者動(dòng)脈彈性的影響，探討替米沙坦對(duì)動(dòng)脈血管彈性病理性降低的逆轉(zhuǎn)機(jī)制。?1方法入選原發(fā)性高血壓患者127例，應(yīng)用替米沙坦80mg·d治療3個(gè)月，測(cè)定患者治療前后血清一氧化氮、血清瘦素水平及
6、觀察大、小動(dòng)脈彈性指數(shù)。結(jié)果替米沙坦治療3個(gè)月，原發(fā)性高血壓患者總體血壓水平下降(P<0.05)，達(dá)到降壓治療的目的。替米沙坦極顯著性降低血清瘦素水平(P<0.01)，顯著提高血清一氧化氮濃度(P<0.05)，并提升大動(dòng)脈彈性指數(shù)和小動(dòng)脈彈性指數(shù)(P<0.01)。結(jié)論替米沙坦能控制原發(fā)性高血壓并改善動(dòng)脈彈性。關(guān)鍵詞：替米沙坦；原發(fā)性高血壓；動(dòng)脈彈性；一氧化氮；瘦素中圖分類號(hào)：R969.4文獻(xiàn)標(biāo)志碼：B文章編號(hào)：1007-7693(2012)06-0554-04EffectofTelmisartanTreatme
7、ntonArteryElasticityinEssentialHypertension*HUANGHanhui,ZHENGShiming,MEIZhengrong,YANPengke(DepartmentofPharmacy,theThirdAffiliatedHospitalofGuangzhouMedicalUniversity,Guangzhou510150,China)ABSTRACT:OBJECTIVETodiscusstheeffectoftelmisartantreatmentonarteryel
8、asticityinessentialhypertension(EH)andtoinvestigatethemechanismoftelmisartanthatreversethepathologicalchangesofarteryelasticity.METHODSTotally?1127patientswithessentialhypertensionwerechosentobe
