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1、AppblicationoflowconcentrationsofcontrastagentslnDSCTcoronaryangiograpphyPostgradute:YahLiangliangTutor:Prof.YangXuehuaRadiologyDepartment,TheFirstAffiliatedHospitalofZhengzhouUniversityZhengzhou,China,450052AbstractObjectiveToinVestigatemevalueoflowconcentrations,lowdoseofcontrastagents肌d】
2、owI"adiationdosecombinedwithsinogram‘a(chǎn)ffirmediteratiVerecons仇lcnon(SAFIRE)improv:ingcoron叫arteryimagequalityandreducingradi燦ndoseandtheiIlcidencerateofcontrastmediuminducednephropathyinsecond。gencranondual.sou∽eCTSequenceorFlashSCanmodeofcoronaryarteD,蚰a粵ng·MethodsThisthesiswasdividedinto2p
3、an&?..Part1:Forty-twopatientswithcoronaryarterydiseasewererandomlyd1ⅥdedmgroupA(370IIlg№1120kV)andgroupB(270mgI/mllOOkV),whichw讎allscaIledinSequencescanmode.TheimagesofgroupBwerereconstructedwnnSAF承E鋤dtakenasgroupC.Thegeneralinformation,SCantime,thedoseotcon咖stagent,th,eeffectiveradiationdo
4、seandcoronaryarteryse舯ent1matgequantyofgroupAandgroupB(C)werecompared.ThecoronaryCTValueaIld1magenoise(SD)weremeatsuredandcomparedinaorta,,leftcoronaryandn曲tcoronary,thenth,eSNRandCNRamongthreegroupswerecalculatedandcomp刪’IIIAbstractPart2:sixty-sixpatientswithcoronaryarterydiseasewererandom
5、lydividedintogroupA(370mgI/ml,60m1)、groupB(370mgI/ml,(weightx0.6)m1)andgroupC(320mgI/ml,(weightx0.Orrd,SAFIRE),whichwereallscanedinFlashspiralscanmode.Thedifferenceofimagequalitywerecomparedamong3groups;ThedifferenceofcoronaryCTvalue,SD,SNRandCNRweremeasuredandcomparedinaorta.1eftcoronaryan
6、drightcoronary.ResultsPart1:Therewerenotstatisticallysignificantinage,BMI,averageheartrate,scantimeandcontrastdosageofgroupAandgroupB(C)(allP>0.05),whiletheED,CTDIvolandthecoronaryarterysegmentimagequalityhadstatisticallysignificant(allP<0.05)。ThecoronaryCTvaluesinaorta,leftcoronaryandright
7、coronaryamongthreegroupswereallnotstatisticallysignificant(allP>0.05),whilethenoise,SNR,CNRhadstatisticallysignificant(allP<0.05).TheimagenoisewasthehighestandSNR,CNRwerethelowestingroupB,andtherewerenotstatisticallysignificantinnoise.SNRandCNRbetweengro