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1、單腔造口與雙腔造口的Meta分析中文摘要單腔造口與雙腔造口的Meta分析中文摘要目的:評(píng)價(jià)單腔造口和雙腔造口的并發(fā)癥發(fā)生風(fēng)險(xiǎn),探討兩種造口方式各自的優(yōu)劣,為臨床應(yīng)用提供參考。方法:檢索PubMed、EMBASE、Springer及NCBI等公共檢索系統(tǒng),文獻(xiàn)搜索截止至2014-02-01,納入文獻(xiàn)時(shí)間跨度從1996-2010年。選擇其中有關(guān)單腔造口和雙腔造口比較的對(duì)比研究,進(jìn)行質(zhì)量評(píng)價(jià)及數(shù)據(jù)提取,對(duì)造口缺血壞死、造口旁疝、造口脫垂、造口周圍感染(皮炎),造口狹窄以及造口回縮進(jìn)行分析。分析軟件為RevMan5.2軟件及STATA11.0。結(jié)果:(1)Meta分析
2、結(jié)果顯示,單腔造口在造口旁疝(RR:0.66,CI:0.49-0.91,Z=2.57,P=0.01)、造口脫垂(RR:0.23,CI:0.05-0.99,Z=1.97,P=0.05)及造口回縮(RR:0.21,CI:0.04-0.99,Z=1.97,P=0.05)方面較雙腔造口風(fēng)險(xiǎn)要小。(2)雙腔造口在造口缺血壞死(RR:5.08,CI:1.94-13.22,Z=3.31,P=0.009)方面更具優(yōu)勢(shì)。(3)而對(duì)于造口狹窄(P=0.32)及造口周圍感染(P=0.09),研究結(jié)果并無(wú)顯著統(tǒng)計(jì)學(xué)意義。結(jié)論:根據(jù)本研究數(shù)據(jù),兩種造口方式各有利弊,單腔造口的并發(fā)癥較雙
3、腔造口而言相對(duì)要少,更有利于術(shù)后患者的回復(fù),在手術(shù)中盡可能保護(hù)造口血供的情況下,我們更推薦單腔造口術(shù)。關(guān)鍵詞:?jiǎn)吻辉炜?;雙腔造口;術(shù)后并發(fā)癥;Meta分析作者:沈一辰指導(dǎo)教師:趙宏IAbstract單腔造口與雙腔造口的Meta分析AbstractObjective:Evaluationoftheriskofcomplicationsbetweenendcolostomyandloopcolostomy.Exploretherespectivemeritsoftwokindsofenterstomy.Providereferenceforclinicalappl
4、icationsMethods:RetrievePubMed,EMBASE,Springer,NCBIandotherpublicretrievalsystems,literaturesearchesasof2014-02-01,thetimeoftheliteratureincludedinspanfrom1996to2010.Selectthecomparativestudyofcomparativeaboutendcolostomyandloopcolostomytoextractthedataandevaluatethequality.WeuesSof
5、twareRevMan5.2toanalyzetheincidenceofthecomplicationsofenterstomy,asstomanecrosis,parastomalhernia,stomaprolapse,peristomalinfection(dermatitis)andstomaretraction.Results:(1)TheMeta-analysisshowthattheendcolostomyhavealowerriskatparastomalhernia(RR:0.66,CI:0.49-0.91,Z=2.57,P=0.01),s
6、tomaprolapse(RR:0.23,CI:0.05-0.99,Z=1.97,P=0.05)andstomaretraction(RR:0.21,CI:0.04-0.99,Z=1.97,P=0.05).(2)Theloopcolostomyisbetteratthegroupofstomanecrosis(RR:5.08,CI:1.94-13.22,Z=3.31,P=0.009).(3)Forstomaprolapse(P=0.32)andperistomalinfection(dermatitis)(P=0.09),thestudydidnotstati
7、sticallysignificant.Conclusions:Eachtypeofdefuncyioningstomahasitsadvantagesanddisadvantages.Thestudyendorsesendcolostomystomaoverloopcolostomy.Accordingtothedata,thecomplicationsofendcolostomywerelessthanthoseofloopcolostomy.Whenthestomabloodwasprotectedaspossible,werecommendtheend
8、colostomy.KeyWords: