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1、5%50%90%100%Chapter18–ClinicalMicrobiology281SevereAcuteRespiratorySyndromeCoronavirusonHospitalSurfacesDowellSF,SimmermanJM,ErdmanDD,etal(CtrsforDiseaseControlandPrevention,Atlanta,Ga;MinistryofPublicHealth,Nonthaburi,Thailand)ClinInfectDis39:652-657,200418–4Background.—Healthcarework
2、erscontinuedtocontractsevereacuterespiratorysyndrome(SARS),evenafterbarrierprecautionswerewidelyimplemented.Methods.—Weexploredthepossiblecontributionofcontaminatedhos-pitalsurfacestoSARStransmissionbyswabbingsurfacesin2hospitalsandtestingtheswabsamplesbyreverse-transcriptasepolymerasec
3、hainreaction(RT-PCR)andviralculture.Results.—Twenty-sixof94swabsamplestestedpositiveforviralRNA.Swabsamplesofrespiratorysecretionsfromeachofthe4patientsexaminedtestedpositivebyRT-PCR,aswere12of43swabsfrompatientroomsand10of47swabsfromotherpartsofthehospital,includingthecomputermousesat2
4、nursingstationsandthehandrailofthepublicelevator.Speci-mensfromareaswithpatientswithSARSinthemostinfectiousphaseofill-ness(days5-15afteronset)weremorelikelytobeRNApositivethanwereswabspecimensfromelsewhere(24of63samplesvs.2of31samples;P.001).Allculturesshowednogrowth.Conclusions.—Altho
5、ughthevirusesidenti?edmayhavebeennoninfec-tious,healthcareworkersshouldbeawarethatSARScoronaviruscancon-taminateenvironmentalsurfacesinthehospital,andfomitesshouldbecon-sideredtobeapossiblemodeoftransmissionofSARS.SARSisalreadyaprettyscaryprospectformostofus,buttheseauthorsare“uppingth
6、eante”byshowingusthatlargedropletspreadordirectcontactmaynotbetheonlywaythisconditioncanbespread.Fomitesandenviron-mentalsurfaceswithinhospitalscanapparentlyalsobeinvolved,providinguswithafurtherjusti?cationforrigorousenvironmentalhygiene.M.G.Bissell,MD,PhD,MPHLimitedValueofRoutineStool
7、CulturesinPatientsReceivingAntibioticTherapyChitkaraYK(CarondeletStMary’sHosp,Tucson,Ariz)AmJClinPathol123:92-95,200518–5Abstract.—Inthelaboratoryinvestigationofsuspectedcommunityac-quireddiarrhea,stoolculturesmaybeorderedonpatientsreceivingantibi-otictherapy.Becausemanyantibio
