資源描述：
《冠狀病毒Coronavirusl論文-2018 Retrospective detection and phylogenetic analysis of swine acute diarrhea syndrome coronavirus in pigs in southern.pdf》由會員上傳分享，免費(fèi)在線閱讀，更多相關(guān)內(nèi)容在學(xué)術(shù)論文-天天文庫。
1、DR.JINGYUNMA(OrcidID:0000-0001-6285-312X)Articletype:OriginalArticleRetrospectivedetectionandphylogeneticanalysisofswineacutediarrheasyndromecoronavirusinpigsinsouthernChina#1,2#1,211,2331,2L.Zhou
2、Y.Sun
3、T.Lan
4、R.T.Wu
5、J.W.Chen
6、Z.X.Wu
7、Q.M.Xie
8、X.B.*1,2,3*1,2Zhang
9、J.Y.MaArticle#Theseauthorscontri
10、butedequallytothiswork.*correspondingauthors.1CollegeofAnimalScience,SouthChinaAgriculturalUniversity,Guangzhou,China2KeyLaboratoryofAnimalHealthAquacultureandEnvironmentalControl,Guangzhou,Guangdong,China3GuangdongWen’sFoodstuffsGroupCo.,Ltd.,Guangdong,ChinaCorrespondenceX.B.Zhang,Collegeof
11、AnimalScience,SouthChinaAgriculturalUniversity,Guangzhou,China.E-mail:zhangxb@scau.edu.cnThisarticlehasbeenacceptedforpublicationandundergonefullpeerreviewbuthasnotAcceptedbeenthroughthecopyediting,typesetting,paginationandproofreadingprocess,whichmayleadtodifferencesbetweenthisversionandthe
12、VersionofRecord.Pleasecitethisarticleasdoi:10.1111/tbed.13008Thisarticleisprotectedbycopyright.Allrightsreserved.J.Y.Ma,CollegeofAnimalScience,SouthChinaAgriculturalUniversity,Guangzhou,China.E-mail:majy2400@scau.edu.cnSummarySwineacutediarrheasyndromecoronavirus(SADS-CoV),anovelcoronavirus,
13、wasfirstdiscoveredinsouthernChinainJanuary2017andcausedalargescaleoutbreakoffataldiarrhealdiseaseinpiglets.Here,weconductedaretrospectiveinvestigationof236samplesArticlefrom45swinefarmswithaclinicalhistoryofdiarrhealdiseasetoevaluatetheemergenceandthedistributionofSADS-CoVinpigsinChina.Ourre
14、sultssuggestthatSADS-CoVhasemergedinChinaatleastsinceAugust2016.Meanwhile,wedetectedaprevalenceofSADS-CoV(43.53%),porcinedeltacoronavirus(8.83%),porcineepidemicdiarrheavirus(PEDV)(78.25%),rotavirus(21.77%)andtransmissiblegastroenteritisvirus(0%),andwealsofoundtheco-infectionofSADS-CoVandPEDV
15、occurredmostfrequentlywiththerateof17.65%.Wescreenedandobtainedtwonewcompletegenomes,fiveNandfiveSgenesofSADS-CoV.PhylogeneticanalysisbasedonthesesequencesrevealedthatallSADS-CoVsequencesinthisstudyclusteredwithpreviouslyreportedSADS-CoVstrainstofo
