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1、兒童紫癜性腎炎41例從“毒”論治研究作者：趙智強，耿珊珊，孫軼秋，郁曉維，韓新民【摘要】目的從“毒”探討兒童紫癜性腎炎的發(fā)病機(jī)理及治療，以探尋新的中醫(yī)病因病機(jī)及治療學(xué)理論。方法回顧江蘇省中醫(yī)院兒科2002-2006年41例兒童紫癜性腎炎住院病例，觀察“毒”的臨床表現(xiàn)，著重從處方藥物組成著手，探討相關(guān)治法。結(jié)果本病具有“毒”的致病特點與臨床表現(xiàn)，“毒”的針對性治療包括解毒（涼血化瘀解毒、活血解毒、清熱解毒、祛風(fēng)解毒、除濕解毒）、排毒（利尿泄毒、通腑泄?jié)幔?、抗毒（益氣、養(yǎng)陰），其配伍多以涼血化瘀解毒為核心。結(jié)論“毒”是本病的重要致病因素之一，從“毒”論治有重要的臨床價值。【關(guān)
2、鍵詞】兒童紫癜性腎炎；毒邪；解毒；排毒；抗毒【Abstract】ObjectiveTostudythepathogenesisandtreatmentofHenoch-SchonleinpurpuraofchildrenfromtoxinandlookfornewtheoryofpathogenyandtherapeuticsinChinesemedicine.Itcanmaketreatmentbytheoryoftoxinbecomeanewwaytoimprovecurativeeffect,shortencourseofthediseaseandreducerec
3、rudescence.MethodsWecollectedthepatientswhowereinhospitalofTCMinJiangsuProvincefrom2002to200612andestablishedstudyingstandards.Weobservedtherelationbetweensymptomandtoxininordertostudypathogenesisoftoxin.Weextractedprescriptionandsummedupdrugsincommonuseandrepresentativetherapeuticsofthat
4、.Weanalyzedtheinternalprincipiumofthetherapeuticsinordertoseekapplyingofdetoxifcation,drainingtoxinandresistingtoxin.ResultsThediseasehasthecharactersandsymptomsoftoxin,andtoxinrunthoughallthecoursesofit.Toxinconsistsofinternaltoxinandexternaltoxin.Externaltoxinincludessix-eviltoxin,foodt
5、oxin,insecttoxinandmedicinetoxin.Intertoxinincludesblood-blacktoxin,wettoxinandheattoxin.Toxinusuallycausesthediseasealongwithwind,heat,blood-blackandwet.Thespecialtherapeuticsoftoxinincludesdetoxifcation,drainingtoxinandresistingtoxin.Thesemethodsarecoolingbloodanddetoxifcation,clearingh
6、eatanddetoxifcation,dispellingwindanddetoxification,diuresisanddetoxifcation.Weusuallyusethreeorfourofthem,sometimesusetwoofthem.Theircoreofmatchusuallyiscoolingbloodanddetoxifcation.Furthermore,weusealongwithothertreatmentaccordingtostate,locationoftheillnessandconstitutionofpatients.Con
7、clusionToxinisoneofpathogenyfactors,wecanstudythepathogenesisfromtoxin,inordertoestablishthenew12theoryofpathogeny,guidetreatmentandimprovecurativeeffect.【Keywords】Henoch-Schonleinpurpuraofchildren;toxin;detoxifcation;drainingtoxin;resistingtoxin紫癜性腎炎是過敏性紫癜最嚴(yán)重的一種并發(fā)癥
