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1、脂溢性角化病的發(fā)病機(jī)理及治療論文廖烈蘭黃光華黃家基毛勝富徐振平脂溢性角化病（SK）是由于角質(zhì)形成細(xì)胞成熟遲緩所致的一種良性表皮內(nèi)腫瘤，又稱老人疣。皮損常好發(fā)于頭、面部，典型的臨床表現(xiàn)為扁平丘疹或斑片，呈淡褐色或深褐色，表面光滑，無自愈傾向。近年，脂溢性角化病有發(fā)病年輕化趨勢，且影響容顏而倍受關(guān)注。本文旨對脂溢性角化病的發(fā)病機(jī)理及治療作一綜述。1病因脂溢性角化病好發(fā)于暴露部位.freelura9通過免疫細(xì)胞和體外細(xì)胞培養(yǎng)的方法發(fā)現(xiàn)，脂溢性角化病患者皮損中P16全層皮膚表達(dá)，而且體外培養(yǎng)的表皮細(xì)胞在孵育3周后依然存活（正常3arksR,Thepreval
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