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1、紅-藍光治療儀聯(lián)合治療尋常瘞瘡療效觀察[摘要]目的:觀察紅-藍光聯(lián)合治療瘞瘡患者的臨床療效。方法:將64例座瘡患者隨機分成2個治療組:①單純藍光照射組(n=36);②紅藍光混合照射組(n=28)。采取連續(xù)4周,每周2次發(fā)光二極管為基礎(chǔ)的座瘡治療儀照射。輕度患者治療一個療程,中、重度座瘡患者連續(xù)治療1?3個療程。結(jié)果:經(jīng)過系統(tǒng)治療后,瘞瘡皮損均有所減輕。兩組總有效率無顯著差別(分別為80.5%及89.3%,P=0.514)。顯效率比較,紅藍光混合照射可達35.7%,遠遠高于單純藍光照射組(8.3%)(P=0.008)。重度座瘡較中度
2、瘞瘡有更為明顯的反應(yīng),且副作用很小,使用藍光對炎癥反應(yīng)可產(chǎn)生效果,配合紅光療效優(yōu)于單獨使用,無明顯的副作用。結(jié)論:紅-藍光聯(lián)合治療瘞瘡可獲得理想療效,適合治療輕、重度瘞瘡患者。[關(guān)鍵詞]藍光;紅光;瘞瘡[中圖分類號]R622[文獻標識碼]A[文章編號]1008-6455(2008)07-1041-03ClinicalstudyofCombinationblueandredLEDphototherapyinthetreatmentofmildtosevereacnevulgarisCHENGBiao,LIQin,LIUHong-we
3、i,JIANGSa,CHENKui,CHENChun(DepartmentofPlasticSurgery,GuangzhouGeneralHospitalofGuangzhouMilitaryRegion,Guangzhou,510010,Guangdong,China)Abstract:ObjectiveToevaluatethetherapeuticeffectoftheblueandredlightcombinationphototherapyforacne.Methods64patientswithmildtosever
4、eacnevulgariswererandomizeddividedintotwotreatmentgroups:bluelight(n=36),mixedblueandredlight(n二28).Allsubjectsweretreatedovereightsessions,twoperweek3daysapart,alternatingbetweenbluelightor/andredlightfromalight-emittingdiode(LED)-basedtherapysystem.ResultsAmeanreduc
5、tioninlesioncountwasobservedatallfollow-uppoints.Nostatisticallydifferencesineffectivenessbetweenthetwodifferentlightsourceswerefound(80.5%vs.89.3%,P二0.514).However,themeanlesioncountreductionwassignificantat8.3%withbluephototherapy,themeanlesioncountreductionwasalsos
6、ignificantat35.7%(P=0.008)withcombinationphototherapy.Severeacneshowedamarginallybetterresponsethanmildacne.Sideeffectswereminimalandtransitory.Specificallybluelighthasamarkedeffectoninflammatoryacnelesionsandseemssufficientforthetreatmentofacne.Inaddition,thecombinat
7、ionofblue-redlightradiationseemstobesuperiortobluelightalone.ConclusionCombinationblueandredLEDtherapyappearstohaveexcellentpotentialinthetreatmentofmildtosevereacne.Keywords:redlight;bluelight;acne瘞瘡是一種多發(fā)生于青春期常見的皮膚疾病,好發(fā)于頰、鼻前端及兩側(cè)、額、下額,胸背部等處,表現(xiàn)為粟粒及綠豆大小的隆起皮疹,加之炎癥反應(yīng)及微生物作
8、用,可演變?yōu)榍鹫?、膿皰及瘢痕,不僅有礙美觀而且給患者造成心理負擔[1]。近年來,使用以發(fā)光二極管(light-emittingdiode,LED)治療系統(tǒng)為基礎(chǔ)的光子瘞瘡治療儀為瘞瘡的治療提供了一個全新的方法[2-3]。2004年5月?2007年5