資源描述：
《阿奇霉素聯(lián)合喜炎平治療小兒支原體肺炎的療效觀察》由會員上傳分享，免費在線閱讀，更多相關內(nèi)容在工程資料-天天文庫。
1、阿奇霉素聯(lián)合喜炎平治療小兒支原體肺炎的療效觀察梁春霞，姜秀鳳，姜徳華(遼寧省普蘭店市中心醫(yī)院藥劑科，遼寧普蘭店116200)［摘要］目的評價阿奇霉索聯(lián)合喜炎平注射液治療小兒支原體肺炎的臨床療效及安全性。方法將98例小兒支原體肺炎患兒隨機分為治療組及對照組。2組患兒均釆用相同的基礎治療，治療組再給予阿奇霉素聯(lián)合喜炎平注射液靜滴治療，対照組只給與同等劑量的阿奇霉素靜滴治療。2組均連續(xù)治療5d,停藥3d后再連續(xù)治療3d。結果治療組總有效率為98%,對照組總有效率為85.7%,治療組總有效率高于對照組(PV0
2、.05)。治療纟R在退熱時間、咳喘消失時間、啰音消失時間、胸片吸收時間及住院時間上均明顯短于對照組(P均<0.01)o2組治療后肺功能均較治療前顯著改善，且治療組改善幅度顯著大于對照組(PV0.05)。2組治療后血清IL?6、IL-8.TNF?ct水平均較治療前顯著改善，且治療組改善幅度顯著大于対照組(P均V0.01)02組不良反應發(fā)牛率比較無顯著性差異(P>0.05),且均為輕度，患兒可耐受。結論阿奇霉索聯(lián)合喜炎平注射液治療小兒支原體肺炎顯苦提高療效，縮短了療程，不良反應少而輕，安全性高，在臨床上值
3、得推廣。［關鍵詞］阿奇霉素；喜炎平注射液；支原體肺炎［中圖分類號］R563.1［文獻標識碼］BObservationofcurativeeffectofAzithromycincombinedwithXiyanpinginjectioninthetreatmentofmycoplasmapneumoniainchildrenLIANGChunxia,JIANGXiufeng,JIANGDehua(LiaoningPuliandianCityZhongxinHospitalDepartmentofpha
4、rmacy,LiaoningPulandian116200China)［ABSTRACT］OBJECTIVEToevaluatetheclinicalefficacyandsafetyofAzithromycincombinedwithXiyanpinginjectionintreatmentofchildrenwithMycoplasmapneumonia.METHODS98casesofchildrenwithmycoplasmapneumoniawererandomlydividedintotr
5、eatmentgroupandcontrolgroup.Twogroupsofchildrenweregiventhesamebasictreatment.TreatmentgroupwasgivenextraAzithromycincombinedwithXiyanpingintravenousinjection.Thetwogroupsweretreatedforcontinuousfivedays,afterstoppingthemedicineforthreedays,thengiveanot
6、herthreedaystreatment.RESULTSThetotaleffectiverateoftreatmentgroupwas98%,controlgroup85.7%,totaleffectiverateinthetreatmentgroupishigherthaninthecontrolgroup(P<0.05).Thetreatmentgroupinabatementtimeoffever,coughdisappearedtime,ralesdisappearancetime,che
7、stX-rayabsorptiontimeandhospitalstayweresignificantlyshorterthanthecontrolgroup(P<0.01).Pulmonaryfunctionoftwogroupsaftertreatmentwasbothimproved,andthetreatmentgroupwasimprovedsignificantlymorethanthecontrolgroup(P<0.05).ThescrumIL-6,IL■&TNF-alevelswer
8、ealsoimproved,andthetreatmentgroupwasimprovedsignificantlymorethanthecontrolgroup(P<0.01)?Adversereactionsoftwogroupshavenosignificantdifference(P>0.05),allofwhichweremild,childrencanbetolerated.CONCLUSIONAzithromycincombinedwith
