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1、中國(guó)當(dāng)代醫(yī)藥2014年6月第21卷第17期·醫(yī)學(xué)檢驗(yàn)·兒童支原體肺炎急性期血清心肌酶譜改變的臨床分析伍春蓉孫志豪1.中山大學(xué)附屬東莞東華醫(yī)院檢驗(yàn)科,廣東東莞523110;2.廣東省東莞市婦幼保健院檢驗(yàn)科,廣東東莞523120【摘要】目的探討兒童支原體肺炎急性期血清心肌酶譜變化及其臨床意義。方法選取2012年8月~2013年8月本院診治的180例支原體肺炎急性期患兒為觀察組,以同期40例健康體檢兒童作為對(duì)照組,分析心肌酶檢測(cè)結(jié)果及其臨床意義;并將觀察組中122例心肌酶譜異常的患兒根椐臨床癥狀分為輕癥組、重癥組,分析心肌酶水平變化情況。結(jié)果觀察組的CK—MB、
2、LDH、CK、Ot—HBDH及AST水平均高于對(duì)照組,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論支原體肺炎急性期患兒存在不同程度的心肌損傷,血清心肌酶CK—MB能特異性反映心肌損傷,并指導(dǎo)進(jìn)一步治療。【關(guān)鍵詞】?jī)和?;支原體肺炎;急性期;心肌酶【中圖分類號(hào)】R446.1[文獻(xiàn)標(biāo)識(shí)碼】A【文章編號(hào)】1674—4721(2014)06(b)一0101—03Clinicalanalys
3、isofserummyocardialenzymechangeinchildrenwithMycoplasmapneumoniaduringtheacuteperiodWUChun—rongSUNZhi—hao21.DepartmentofLaboratory。DonghuaHospitalAffiliatedtoZhongshanUniversity,Dongguan5231lO,China;2.Depart—mentofLaboratory,MaternalandChildHealthHospitalofDongguanCityinGuangdongP
4、rovince,Donggnan523120,China【Abstract]ObjectiveTostudythechangeandclinicalsignificanceofserummyocardialenzymeinchildrenwithMy-coplasmapneumoniaduringtheacuteperiod.MethodsThe180childrenofpatientswithMycoplasmapneumoniadur-ingtheacuteperiodand40healthexaminationchildreninourhospita
5、lduringtheperiodfromAugust2012toAugust2013wereselectedasobservationgroupandcontrolgrouprespectively,andclinicalsignificanceofmyocardialenzymetestresultswereanalysed.122casesofmyocardialenzymechildreninobservationgroupweredividedintomildgroupandseveregroupaccordingtoclinicalsymptom
6、,thechangeofmyocardialenzymelevelwasanalysed.ResultsCK—MB,LDH,CK,ct-HBDH,ASTinobservationgroupwashigherthanthatincontrolgrouprespectively,withstatisticaldiffer—ence(P<0.05).CK-MB,LDH,CK,c~-HBDH,ASTinseveregroupwashigherthanthatinmildgrouprespectively,withsta-tisticaldifference.05)
7、.Myocardialenzymesinrecoverygroupofchildrenwithhighmyocardialenzymeandcontrolgroupwascomparedrespectively,withnostatisticaldifference(P>0.05).ConclusionMycoplasmapneumoniaeinchil—drenwithacutemyocardialdamageofdifferentlevel,serumCK-MBcouldspecificallyreflectmyocardialdamageandtog
8、uidefurthertreatment.【Keywords】Ch